University Report: Continuous Flow Synthesis of Molecules

This report examines the application of continuous flow chemistry for the synthesis of complex functional molecules, highlighting its advantages over traditional batch processes. It discusses the use of microreactors to enhance reaction monitoring and improve product yields, addressing challenges related to scale-up and process design. Case studies and examples, including drug synthesis, photochemistry, and multi-step chemical conversions like the Curtius rearrangement, are presented to illustrate the practical applications of flow synthesis. The report also covers transport phenomena in continuous flow reactors, scale-up issues, and the integration of flow chemistry processes, such as the synthesis of butane-2,3-diacetal protected diols and 3-nitropyrrolidine building blocks. Ultimately, it emphasizes the importance of continuous flow chemistry in modern organic synthesis for its efficiency, safety, and sustainability.