This case study analyzes the case of Mrs. Brown, who presented with symptoms indicative of systolic heart failure. The analysis begins with the diagnosis, exploring the pathophysiology of the condition, including reduced cardiac muscle efficacy, potential causes like myocardial infarction, and the impact on the cardiac cycle. The study then delves into the patient's symptoms, such as severe dyspnea and pulmonary edema, linking them to physiological mechanisms like allergen responses and reduced ventilation capacity. It also discusses the effects of decreased oxygen delivery and hypoxemia. The case study further examines the activation of the renin-angiotensin-aldosterone system and the sympathetic nervous system as contributing factors. The second part focuses on vital signs, identifying abnormalities in blood pressure, respiratory rate, pulse rate, and oxygen saturation. It prioritizes interventions such as oxygen administration and positioning to address hypoxemia and respiratory distress. The final part explores the use of medications like Furosemide and GTN, explaining their mechanisms of action and potential adverse effects. The case study references multiple research articles to support the analysis and recommendations.