Australian Catholic University BIOL122 Assignment 2 Vodcast: Diabetes

This assignment presents a 5-minute Vodcast on Type 2 Diabetes Mellitus, focusing on the pathophysiology and pharmacological management for a specific 'person/client.' The assignment, part of Australian Catholic University's BIOL122 Human Biological Science 2 course, requires students to demonstrate effective communication through video, audio, and written content. The student's solution incorporates research from various sources, including Abdul-Ghani & DeFronzo (2018), DeFronzo (2018), Mann et al. (2017), Maruthur et al. (2016), and Miranda-Diaz et al. (2014), to provide a comprehensive overview of the disease, its progression, and the impact of different treatments, such as insulin and metformin, on patients. The solution also addresses how hyperglycemia leads to other complications such as myocardial infarction and neuropathy. The assignment is designed to assess students' understanding of a National Health Priority Area and their ability to present scientific information in an accessible format.

Abdul-Ghani, M., & DeFronzo, R. (2018). Therapeutic strategies for type 2 diabetes
mellitus patients with very high HbA1c: is insulin the only option? Annals of Translational
Medicine, 6(S2), S95-S95. doi:10.21037/atm.2018.11.15
This article was quite important for my research. It provided important information about the
importance of HbA1c in long term management of type 2 diabetes.
DeFronzo,R. A. (2018). Pathogenesis of Type 2 Diabetes Mellitus. Endocrinology, 1-74. doi:
10.1007/978-3-319-27317-4_8-1
I used this journal to get information about the pathophysiology of type 2 diabetes. This is where
I got information when comparing insulin synthesis and resistance.
Mann, J. F., Ørsted, D. D., Brown-Frandsen, K., Marso, S. P., Poulter, N. R., Rasmussen, S.,
… Buse, J. B. (2017). Liraglutide and Renal Outcomes in Type 2 Diabetes. New England
Journal of Medicine, 377(9), 839-848. doi:10.1056/nejmoa1616011
I used this article to obtain information on how hyperglycemia leads to myocardial infarction.
Maruthur,N. M., Tseng, E., Hutfless, S., Wilson, L. M., Suarez-Cuervo, C., Berger, Z., …
Bolen, S. (2016). Diabetes Medications as Monotherapy or Metformin-Based Combination
Therapy for Type 2 Diabetes. Annals of Internal Medicine, 164(11), 740. doi:10.7326/m15-
2650
I used this article to get information on the mechanism of action of metformin.
Miranda-Diaz,A. G., Roman-Pintos, L. M., Rodriguez-Carrizalez, A. D., Troyo-
Sanroman, R., Alatorre-Carranza, M. D., Cardona Muñoz, E. G., & Hernandez-Ojeda, J.

(2014). Effect of rosuvastatin on diabetic polyneuropathy: a randomized, double-blind,
placebo-controlled Phase IIa study. Diabetes, Metabolic Syndrome and Obesity: Targets and
Therapy, 401. doi:10.2147/dmso.s65500
In this article, I obtained information on how hyperglycemia leads to a condition known as
neuropathy.