This report analyzes a case of a 75-year-old patient, Mr. Kirkmann, who presented with a urinary tract infection and later developed sepsis. The report delves into the pathogenesis of urosepsis, discussing how bacterial infections in the urinary system can lead to a systemic inflammatory response. It examines the role of endotoxins, the immune system's reaction, and the resulting clinical manifestations. Furthermore, the report identifies and justifies an appropriate nursing strategy for managing the patient's condition, specifically focusing on vasopressor therapy, and provides the rationale behind this choice. The report then critically analyzes Mr. Kirkmann's arterial blood gas results, interpreting the abnormal values in relation to the underlying pathogenesis and the physiological changes associated with sepsis, such as tissue perfusion and acid-base imbalances. The conclusion summarizes the key findings and emphasizes the need for further research to improve treatment outcomes for urosepsis.