Application of Genetic Engineering in Medicine

Running Head: APPLICATION OF GENETIC ENGINEERING IN MEDICINE
APPLICATION OF GENETIC ENGINEERING IN MEDICINE
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APPLICATION OF GENETIC ENGINEERING IN MEDICINE1
Abstract:
Genetic engineering is considered as a process, which helps in the alteration of the genetic
composition of an organism. This process is carried on with either by introducing DNA or
removing a part of it. This results in the production of a genetically modified organism. This
process acts to be much faster and prevents the transfer of undesirable genes into the breeding
process. The paper below discusses the application of genetic engineering in the preparation of
Human Insulin.

APPLICATION OF GENETIC ENGINEERING IN MEDICINE2
Table of Contents
Introduction:....................................................................................................................................3
Discussion:.......................................................................................................................................3
Relationship between Insulin and Diabetes:................................................................................3
E.coli & its contribution to the production of Human Insulin:....................................................4
Human Insulin Gene:...................................................................................................................5
Production of Human Insulin Gene:............................................................................................6
Application of Human Insulin Gene into the E.coli Plasmid:.....................................................7
Rationale proving the need for modification:..............................................................................8
Success rate of the modification:.................................................................................................9
Future prospects:..........................................................................................................................9
Conclusion:................................................................................................................................10
References:....................................................................................................................................11

APPLICATION OF GENETIC ENGINEERING IN MEDICINE3
Introduction:
Genetic engineering is considered as a process, which helps in the alteration of the
genetic composition of an organism. This process is carried on with either by introducing DNA
or removing a part of it. This results in the production of a genetically modified organism. This
process acts to be much faster and prevents the transfer of undesirable genes into the breeding
process. Genetic engineering has been applied in various fields such as the medicine, agriculture,
industrial biotechnology and had been the hot topic for scientific research. The paper below
discusses the application of genetic engineering in the preparation of Human Insulin by
genetically modifying E.coli (Baeshen et al., 2015). This was a huge milestone in the production
of insulin on a substantial basis and is the most researched and talked about topic for genetic
engineering. (Baeshen et al., 2014).
Discussion:
Relationship between Insulin and Diabetes:
Insulin is a type of hormone secreted from the pancreas, which helps in regulating the
amount of glucose or sugar from the carbohydrates derived from the food eaten. Thereby, the
insulin helps in regulating the blood sugar level from low to getting to high.