This case study provides insights into the pathophysiology, risk factors, treatment, assessment, and nursing interventions for angina. It also discusses the administration of sublingual glyceryl trinitrate and findings in the ECG. Find all the information you need for your study on angina at Desklib.
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Running head: CASE STUDY ON ANGINA Case study on Angina Name of the Student Name of the University Author Note
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2CASE STUDY ON ANGINA 1.1 Pathophysiology of Angina The term angina is also referred to as angina pectoris that is another form of chest pain due to inadequate blood flow to the cardiac muscle of the body. It is generally found that, any obstruction in the coronary arteries and arterioles can cause the problem of angina among the patients. The oxygen deprivation in the cardiac muscle is due to mainly the formation of atherosclerosis plaques in the coronary arteries. The early stage of the plaques formation is resulted in for the deposition of fatty acid streak. The fatty acid streak is deposited on the intimal surface of the blood vessels and from this early stages of fatty acid streak, advanced atherosclerosis plaques are formed (Hall, 2015;Da Costa et al., 2016). This formation of plaques in the blood vessels restricts the blood flows towards the heart and as a result, adequate amount of oxygen cannot be supplied to the cardiac muscles and angina pectoris takes place. In this case study it is observed that John is 84 year old man who is admitted to the hospital with the problem of cellulitis in his left leg. Along with this, he has past history of hypertension, angina and hypercholesterolemia.From the case study it is noted that, John is a regular smoker and he smoked 20 cigarettes daily. In various studies it is reported that, the practice of smoking is associated with the formation of atherosclerosis plaque in the blood vessels. During the assessment a few vital signs such as blood pressure, pulse rate are recorded (Ford et al., 2018). Risk factors There are a few risk factors that can promote the onset of angina among patients. For example it can be said that diabetes mellitus, smoking, age of the person (More than 45 in case of male), hypertension, family history of cardiovascular disease, lack of physical activity can be counted as major risk factors of angina (Bohm,Reil, Deedwania, Kim & Borer,2015). Therefore, in this case ,it is noted that,John has history of hypertension, practice of serious
3CASE STUDY ON ANGINA smoking and more over John is 64 year old which is one of the risk factor of the disease (Madias, 2018). Treatment of Angina In the treatment of angina, most specifically nitro-glycerine can be uses as it is a vasodilator and will enhance the blood flow by increasing the diameter of the vessels. In addition, calcium channel blocker and beta-blocker are also prescribed to reduce the work load of the heart (Ferrari et al., 2018;Maughan et al., 2018). In case of John, it is reported that, doctor has prescribed metoprolol which is a beta blocker, glyceryl trinitrate that is the medicationofanginaandpravastatinandthelastoneisusedfortreating hypercholesterolemia which is one of the major reason of plaques formation (Ferrari et al., 2018). 1.2Assessment of Chest Pain The chest pain is one of the most common problems in the emergency department of the hospitals in a worldwide manner. It is very crucial to assess the severe chest pain in the early stage of the pain in order to start the treatment as soon as possible. As an untreated chest pain can create severe consequences regarding heart disease. The nursing assessment for the chest pain are as follows- The nurse can use the ‘OLD CARTS’ during the assessment of the pain. In this technique, the nurse at first will assess if there is any history of injury related pain or not as it is sometimes observed that, although the pain is characterized as chest pain, but the actual is pain is due to any previous injury. In this case, no such previous pain is reported. After that, the exact location of pain will be assessed in order to identify the pain, whether it is an ischemic chest pain or not. Then the duration and character of the pain will be assessed. In this case, according to John, the pain is severe in nature.Along with this, the nurse can use the pain scores to know the severity of the pain (Cullen et al., 2014;Widmer et al., 2017).
4CASE STUDY ON ANGINA Anotherimportantassessmenttechniqueforthechestpainistheuseof electrocardiography (ECG) as it is the primary assessment procedure for the patients with the chest pain. ECG is a very effective techniques for patients who are facing severe chest pain. The technique can provide high-yield information about the condition of the patients’ cardiovascular system and a result, the initial management and prognosis will be a little easy for the nurse practitioners (Abid et al., 2015;Abawi et al., 2016). In case of John, the ECG will be effective as it is important to know about the condition of the cardiovascular system of John.Any severe changes in the ECG can be a serious signs of severe condition of the cardiovascular system of the body(Gentry,Mentz, Hurdle & Wang,2016). The American college of Cardiology also recommends echocardiography for the assessment of chest pain patients. In case of John, the nurse can use this techniques as John has previous history of hypertension and this technique is generally used for those who have previous history of cardiovascular problems. Hypertension is counted as a major symptoms of cardiovascular disease (Abid et al., 2015;Brinkert et al., 2017; Werdan et al., 2016). Nursing Interventions After assessing the condition of the patients, the nurses should take steps for managing the condition of the patients. As a part of this, the nurses can start medication in order to give relief to the patients. In case of John, the interventions other than the pharmacological interventions will be discussed. The nursing interventions are as follows- In case of John, the nurses should immediately initiate the ‘OLD CART’ technique. The nurse should ask John about the location of the pain so that the nurse can be sure about the type of pain whether it is ischemic pain or not. After that, she should use the chest pain scale so that the nurse can assess the severity of the pain. Along with this, the facial expression of the patients should also be assessed in order to judge the severity of the pain.
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5CASE STUDY ON ANGINA The nurse should tell the patient to stop all the activities. In addition to this, it should be recommended that, the patient will take rest in the bed in a semi-flower position (Mastue et al., 2017). The nurse should also look after patients pain in an hourly manner so that any improvement or deteriorate condition can be observed among in the patient. The nurses should also take care about the anxiety of the patient. It may happen that, due to the during the ECG, the patient may have anxiety due to the technique. As a part of the nursing intervention, the nurse should take initiatives for reducing the anxiety of the patients. In case of John, it may possible that, the John may feel anxiety (Cohen et al., 2015). So it is very crucial to reduce the anxiety of John. Along with this, echocardiography will also be performed as a part of the assessment plan. So, during this assessment process, again John may feel anxiety and it is the duty of the nurses to reduce it(Nezamzadeh et al., 2012). Another nursing intervention for after the assessment of the chest pain is the raising of awareness among the patients and among their family. The enhanced awareness among the patients and their family will help to manage the stress and anxiety among the patients (Tummala & Farshid, 2015). This technique can be applied in case of John as he has no adequate knowledge related to the assessment technique. So a proper knowledge about the chest pain assessment will allow the patient to assess the problem in a proper way. 1.4 Administration of Sublingual Glyceryl Trinitrate As a part of the John’s treatment, it is observed that, he is prescribed to take glyceryl trinitrate as a spray for his angina. The sublingual administration of the drug through sublingual method will cause direct vasodilation and causes reduction in systemic vascular resistance that is the after load. This administration of drugs will cause dilation of venous and arterial beds. The dilation of the post capillary beds will cause peripheral pooling of bloods.
6CASE STUDY ON ANGINA As a result, the venous returns are lowered and the end diastolic pressure is reduced. Arteriolar relaxation in the cardiovascular system lowers the systematic vascular resistance and the consumption of myocardial oxygen is decreased by the effect of the glyceryl trinitrate ( Hope et al., 2014). Benefits Inthehumanbody,theliverisassociatedwiththedetoxificationofvarious exogenous agents that are present in the blood. In the liver, those exogenous agents go through the process of breakdown as a part of the first pass effect. However, if the glyceryl trinitrate is administered orally most of the drugs molecule will be metabolized due tothe first pass effect of the liver. Asthe drug is administered sublingually, the drug is absorbed in the blood directly and the there is no first pass effect of the liver. So the drug can exert its function maximally. Along with this, there is no harm is associated with this as it is not an invasive technique (Bind, Gnanarajan & Kothiyal, 2017). Risks During the administration the person may swallow the medicine and it will reduce the effect of the medicine (Valensise, Presti & Spaanderman, 2018). Contradiction Duringadministration,itshouldbecarefullynotedthat,thepatienthasno hypersensitivity issue regarding this drugs. The drugs that may cause hypersensitivity are ethanol, peppermint oil. In case of severe hypotensive condition, this drug should not be prescribed at all. In addition, patientswith hypotensive shock, brain trauma, cerebral haemorrhage, anaemia, cardiogenic shock and toxic pulmonary oedema should not be given at all (Valensise, Presti & Spaanderman, 2018).
7CASE STUDY ON ANGINA 1.5 Finding in the ECG In the ECG of the John it can be found that, the nature of the ECG is not normal at all. In a normal ECG, the prominent presence of the QRS segment and a small P and T wave can be reported. A normal ECG curve can indicate a well condition of the heart of the patients. In this ECG of John, it can be noted that, there is prominent P wave in the ECG. After that it is observedthat a ST segment of the ECG is elevated. Due to the deprived oxygen supply to the cardiac cells, ischemic necrosis may happen in the myocardial tissues of the heart. As a result, the infracted cells become less negative due to increased potassium efflux. During the ventricular repolarization, the current flows more to the unaffected areas of the tissues. Hence the reduction of the TQ segment and elevation of ST segments occur. In case of John, it is very crucial to report immediately as it is the indication of STEMI that is ST elevated myocardial ischemia (Hall, 2015).
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8CASE STUDY ON ANGINA References Abawi, M., Nijhoff, F., Stella, P. R., Voskuil, M., Benedetto, D., Doevendans, P. A., & Agostoni, P. (2016). Safety and efficacy of a device to narrow the coronary sinus for the treatment of refractory angina: a single-centre real-world experience.Netherlands HeartJournal,24(9),544-551.URL: https://link.springer.com/article/10.1007/s12471-016-0862-2 Abid, S., Shuaib, W., Ali, S., Evans, D. D., Khan, M. S., Edalat, F., & Khan, M. J. (2015). Chest pain assessment and imaging practices for nurse practitioners in the emergency department.AdvancedEmergencyNursingJournal,37(1),12-22.Doi- 10.1097/TME.0000000000000048 Bind, A. K., Gnanarajan, G., & Kothiyal, P. (2017). A review: sublingual route for systemic drug delivery.International Journal of Drug Research and Technology,3(2), 5. Retrievedfrom-http://www.ijdrt.com/drug-research-and-technology/article/view/a- review-sublingual-route-for-systemic-drug-delivery Böhm, M., Reil, J. C., Deedwania, P., Kim, J. B., & Borer, J. S. (2015). Resting heart rate: risk indicator and emerging risk factor in cardiovascular disease.The American journal of medicine,128(3), 219-228. DOI: Brinkert,M.,Southern,D.A.,James,M.T.,Knudtson,M.L.,Anderson,T.J.,& Charbonneau, F. (2017). Incidence and prognostic implications of late bleeding after myocardial infarction or unstable angina according to treatment strategy.Canadian JournalofCardiology,33(8),998-1005.DOI: https://doi.org/10.1016/j.cjca.2017.05.001
9CASE STUDY ON ANGINA Cohen, B. E., Edmondson, D., & Kronish, I. M. (2015). State of the art review: depression, stress, anxiety, and cardiovascular disease.American journal of hypertension,28(11), 1295-1302. DOI:doi.org/10.1093/ajh/hpv047 Cullen, L., Greenslade, J. H., Than, M., Brown, A. F., Hammett, C. J., Lamanna, A., ... & Parsonage, W. A. (2014). The new Vancouver Chest Pain Rule using troponin as the only biomarker: an external validation study.The American journal of emergency medicine,32(2), 129-134. DOI: http://dx.doi.org/10.1016/j.ajem.2013.10.021 Da Costa Martins, P. A., Juni, R., Duygu, B., Bitsch, N., De Windt, L. J., Vitale, S., ... & Zuchi, C. (2016). Microvascular Angina: Diagnosis and Treatment Particularities. CardiovascularResearch,111(suppl_1),S12-S13.DOI: https://doi.org/10.1093/cvr/cvw131 Ferrari, R., Camici, P. G., Crea, F., Danchin, N., Fox, K., Maggioni, A. P., ... & Lopez- Sendon,J.L.(2018).Expertconsensusdocument:A'diamond'approachto personalized treatment of angina.Nature Reviews Cardiology,15(2), 120. DOI: 10.1038/nrcardio.2017.131Pu Ferrari, R., Pavasini, R., Camici, P. G., Crea, F., Danchin, N., Pinto, F., ... & Fox, K. (2018). Anti-anginal drugs–beliefs and evidence: systematic review covering 50 years of medicaltreatment.Europeanheartjournal,40(2),190-194. doi.org/10.1093/eurheartj/ehy504 Ford, T. J., Corcoran, D., & Berry, C. (2018). Stable coronary syndromes: pathophysiology, diagnosticadvancesandtherapeuticneed.Heart,104(4),284-292.DOI: http://dx.doi.org/10.1136/heartjnl-2017-311446
10CASE STUDY ON ANGINA Gentry, J. L., Mentz, R. J., Hurdle, M., & Wang, A. (2016). Ranolazine for treatment of angina or dyspnea in hypertrophic cardiomyopathy patients (RHYME).Journal of the AmericanCollegeofCardiology,68(16),1815-1817.URL: http://www.onlinejacc.org/content/accj/68/16/1815.full.pdf Hall, J. E. (2015).Pocket Companion to Guyton & Hall Textbook of Medical Physiology E- Book.ElsevierHealthSciences.URL:https://books.google.co.in/books? hl=en&lr=&id=4SR1CQAAQBAJ&oi=fnd&pg=PP1&dq=Pocket+Companion+to+G uyton+%26+Hall+Textbook+of+Medical+Physiology+E-Book.+&ots=- vS9Uq4ADd&sig=D-L3fOxaHPyciF5eQu_0vCDMaA8#v=onepage&q=Pocket %20Companion%20to%20Guyton%20%26%20Hall%20Textbook%20of%20Medical %20Physiology%20E-Book.&f=false Madias, J. E. (2018). Pathophysiology of takotsubo syndrome: do not forsake coronary vasospasm!.Internationaljournalofcardiology,266,42.DOI: https://doi.org/10.1016/j.ijcard.2018.02.002 Matsue, Y., Damman, K., Voors, A. A., Kagiyama, N., Yamaguchi, T., Kuroda, S., ... & Inuzuka,Y.(2017).Time-to-furosemidetreatmentandmortalityinpatients hospitalizedwithacuteheartfailure.JournaloftheAmericanCollegeof Cardiology,69(25), 3042-3051. DOI: 00http://dx.doi.org/10.1016/j.jacc.2017.04.042 Maughan, J., Wei, J., Jones, E., Merz, C. N. B., & Mehta, P. (2018). Endothelial Dysfunction andCoronaryMicrovascularDysfunctioninWomenWithAnginaand Nonobstructive Coronaries. InEndothelium and Cardiovascular Diseases(pp. 555- 562). Academic Press. DOI: https://doi.org/10.1016/B978-0-12-812348-5.00037-4 Nezamzadeh, M., Khademolhosseini, S. M., Mokhtari Nori, J., & Ebadi, A. (2012). Design of guidelines evidence-based nursing care in patients with angina pectoris.Iran J Crit
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11CASE STUDY ON ANGINA CareNurs,4(4),69-76.URL:http://citeseerx.ist.psu.edu/viewdoc/download? doi=10.1.1.940.195&rep=rep1&type=pdf Tummala, S. R., & Farshid, A. (2015). Patients’ understanding of their heart attack and the impact of exposure to a media campaign on pre-hospital time.Heart, Lung and Circulation,24(1), 4-10. DOI: http://dx.doi.org/10.1016/j.hlc.2014.07.063 Valensise, H., Presti, D. L., & Spaanderman,M. (2018). Vasodilatation19.Maternal Hemodynamics,193.URL:https://books.google.co.in/books? hl=en&lr=&id=fyVTDwAAQBAJ&oi=fnd&pg=PA193&dq=Valensise,+H.,+Presti, +D.+L.,+%26+Spaanderman,+M.+(2018). +Vasodilatation+19.+Maternal+Hemodynamics,&ots=xvW5qkZPBi&sig=huPjSwvg wECQMmaTLL2mXeFJ5gQ Werdan, K., Perings, S., Köster, R., Kelm, M., Meinertz, T., Stöckl, G., & Müller-Werdan, U. (2016). Effectiveness of ivabradine treatment in different subpopulations with stable angina in clinical practice: a pooled analysis of observational studies.Cardiology, 135(3), 141-150. DOI:https://doi.org/10.1159/000447443 Widmer, R. J., Lerman, L. O., & Lerman, A. (2017). The Rho (ad)-kinase for individualized treatment of vasospastic angina.European heart journal,39(11), 960-962. DOI: https://doi.org/10.1093/eurheartj/ehx757