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Cytokines and Chemokines Assignment PDF

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Added on  2021-02-05

Cytokines and Chemokines Assignment PDF

   Added on 2021-02-05

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CYTOKINES AND CHEMOKINESLecture 1 and 2
Cytokines and Chemokines Assignment PDF_1
ACTIONS RESULTSACTIVATESSTIMULATESPROLIFERATEDIFFERENTIATEPROMOTESSTRONG ACTIONKILL, LYSE, HELPCALL ON YOUR FRIENDSRECRUIT, HELPSECOND ROUNDSECONDARY RESPONSEMEMORYHITS INSULTSSPECIFICITY
Cytokines and Chemokines Assignment PDF_2
The immune system is divided into those which are static,or innate to theorganism,and those which are responsive,oradoptive to a potentialpathogen or foreign substance.The innate system of immunity is an evolutionary term, the older system thatforms the first line of defence. It is non-specific and the resistance is static (itdoesnotimprove with repeated exposure and there isno memory onsubsequentexposures).This includes physicaldefences such as skin andepithelial surfaces, cilia, commensual flora, acidic gastric contents, fever etc.Others are biochemicaldefences such as soluble -lysozyme,acute phasereactants and complement.The adaptive system is the second line of defence and is activated once theinnate system has been overwhelmed. It is specific to the infective agent andcan store the information aboutthe invaderasmemoryto show anenhanced response to subsequent challengeINNATE AND ADAPTIVE IMMUNE SYSTEMS
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Helper T LymphocytesCytotoxic T LymphocytesINNATE AND ADPTIVE IMMUNE CELLS AND MOLECULES
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1.Elimination ofmicrobialagentsthrough nonspecific protectivemechanisms of the innate immune system.2.Instructions from the innate immune system inform the cells ofthe adoptive immune system as to whether it is appropriate tomake a response and what type of response to make.3.Cells of the adoptive immune system display exquisitely specificrecognition of foreign antigens and mobilize potent mechanismsfor elimination of microbes bearing such antigens.4.The immune system display memory of its previous responses.5.Tolerance of self antigens (Self versus Non Self Discrimination).MAJOR PRINCIPLES OF IMMUNOLOGY
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Cytokines and Chemokines Assignment PDF_6
Hemopoiesis(hematopoiesis)istheprocess by which immature bone-marrow(BM)-derived precursor cells develop intomature blood cells.A single type of stemcellgives rise to allmature blood cells inthebody.Thisstem celliscalled thepluripotentialstem cells.Inthebonemarrow the stem cellthatgivesrise toblood cells is called multipotentHEMOPOIESIS
Cytokines and Chemokines Assignment PDF_7
Natural KillerAntibody=Immunoglobulin (Ig)
Cytokines and Chemokines Assignment PDF_8

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