1MEDICAL Introduction With the emergence of technological advancement the competition between the healthcare organizations in the healthcare industry has got increased to a great extent. Innovation is being considered to be one of the most efficient tools for an organization in order to deal with enhanced competition as well for enhancing consumer satisfaction and profit margin. The open innovation strategy is gaining popularity in current industries including the pharmaceutical industry. The chief reason behind this this innovation technique has made it possible for the organization to leverage.Useful knowledge scattered among firms, universities, individuals and the public domain so that competitive advantage can be gained.In the following essay explanation of the reason behind applying the open innovation model byEli Lilly’s Open Innovation Drug Discovery platformhas been conducted. 1.What is open innovation? Provide a concise summary of the theory. The term open innovation refers to the usage of purposive inflows as well as outflows of knowledge within an organization for accelerating internal innovation along with expanding the market for external usage of the innovation. According to researcher, once an organization adopts the open innovation strategy, the boundaries of the organisation become highly permeable (Bogers, Chesbrough and Moedas 2018). This in turn, allows the organization to combine the resources with external co-operators. In a nutshell, the open innovation strategy can be defined as the process of combining the internal resources with the external resources for boosting the innovative culture within an organisation. One of the major examples of implementation of the open innovation strategy is Microsoft. This company possess more than 10 value pools that includestart-ups,thinksuppliers,consumersanduniversitiesforconsideringtheiropen innovative effort. . Thus it can be said that the open innovation model is a business s model that
2MEDICAL encourages and enables an organization to connect with the outside sources so that new product opportunities, higher pool of talent can be collaborated with in order to ensure enhancement of recognition and profit margin. According to the open innovation theory, all the organizations possess the capability and hence should use external ideas along with internal ideas and internal and external paths to the market for ensuring technological advancement. The strategy of open innovation is confined within the firm but is also included user innovators, creative consumers as well as communities. The chief idea of the management that implement the open innovation strategy in an organization is that in thiseraoftechnologywhereknowledgeiseasilyaccessibleandiswidelydistributed, organizations cannot afford to rely completely in their own research for retaining as well as enhancing their performance. Hence organizations opting for implementation of open strategy tend to buy or licence processes of innovation from other organizations. This process is termed as inbound open innovation. On the other and, internal innovation that are not being used by an organization I also taken outside the form through joint ventures, spin offs or licencing. This process is known as outbound open innovation. For decades, organizations have been using the vertical integration approach where the internal research and development activities result in development of products which are then distributed by the organization. Some of the major benefits of implementing an open innovation strategy by organizations are as follows: a.Innovatingoldproductsaswellasservices:Olderservicesprovidedby organizations often possess the potential to be better in order to attract consumers. Open innovative strategy ensures implementation of a creative team in order to improve the service as per the demand of the consumer.
3MEDICAL b.Decrement and sharing of R&D risks and costs: open innovation enables the organization for sharing the risks as well as the costs of their Research and development processes. Shared partnership on the other hand results in more skills technologies, human capital and resources. This in turn results in significant decrement of expenditure that is needed for ensuring specific pre-determined projects. c.Faster R&D process: Another way the Open innovation strategy and help the organization is by expediting their time to the market. An business can select to acquire valuable technology with the help of in licensing or a purchase of ownership rights rather than losing precious time in developing is own substituent of technology. Thus, this approach is considered to be highly valuable specially in industries like healthcare and information technology. d.Leveraging instruments: Open innovation possess the potential of creating a pool of possibly for influencing the state of the market along with the behaviour of other predominant factors in the commercial environment. One of the major instances of leveraging instrument includes patent pools. In patent pools, a good amount of valuable IP gets shared amongst the members. This process has the potential of producing technological breakthroughs that can create new ones. 2.WhatisOIDD?Describethestructureandfeaturesofthisopeninnovation platform, how it worked and evolved, success factors, and performance. The Open innovation Drug Discovery (OIDD) platform has been launched by a highly popular American pharmaceutical organization named “Elli Lilly and Company. The OIDD platform has been designed for tackling different types of barriers that comes in the way of innovation with
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4MEDICAL the help of identifying of novel molecules that are active in disease biological molecules. The OIDD program possesses the potential to facilitate access to the previously untapped molecules that can help for searching innovative pharmaceuticals. According to the researchers the gap in innovation when it comes to drug discovery researchers, is highly evident (Bogers et al. 2017). The challenges faced by pharmaceutical organizations for identifying the new molecular scaffolds for unprecented biological target can be considered as the key contributor to the hindrance that affects efficient drug discovery. Not only this, another research gap that is faced by the researchers isif there is adequate overlay between drug that includes chemical space as well as biologically active chemical space for providing adequate substrate for drug discovery efforts in future. Considering the fact that it is not possible for a single chemical library to cover the chemical space practically, Elli Lilly has established the OIDD platform. The mentioned platform allows researchers for submittig compounds in order to evaluateproprietarybiologicalassays.Thisprogramhasbeendesignedforencouraging collaboration between the organization’s researcher and external researcher for accessing the novel chemical diversity that are present in individual research laboratories across the world (Carroll et al. 2017). With the help of providing a secure platform that possess the potential to protect intellectual property, the OIDD program is found to be lowering the barrier associated with collaboration between the researchers who are working in different organizations. The OIDD program provides the affiliated researchers with the opportunity for uncovering the possible biological activities of the novel chemical structure along with testing experimental hypothesis. The structure of the OIDD program includes a web-based interface that acts as the central point for connecting external scientists with the scientists who work for the organization with the help
5MEDICAL of the secure portal, all the participants can upload as well as submit structures of the compound that needs to be evacuated for novelty and possess reasonable drug like characteristics. For a molecule to be selected, the researchers need to submit the physical sample to the organization to test. In exchange of the submission, the researcher obtains a report of the biological data that ha beengenerated, once the data gets generated, it is time for the organization to decide whether to continue the collaboration or not (Chesbrough 2017). The panel of proprietaryIn vitro biological assaysis considered to be the experimental centre piece of the OIDD program. These assays have been organized in the modules that are aligned with internal scientific researchers. According to researcher, the Lilly’s OIDD platform has brought about great success the world of pharmaceuticals.TheOIDDmodelhasbeenconstructedbasedonthesuccessofthe PhenotypicDrug DiscoveryInitiative of the company. The mentioned initiative has been taken by the company in the year 2009 for facilitating researchers on molecules across the world that possess the potential to be developed in to medicines.A group at Pfizer has described an application of desirability functions to prioritize compounds with a greater chance of success against a central nervous system (CNS) target (Chesbrough, Lettl and Ritter 2018).A good number of novel structures can be found to have the potential to be converted in to medicines. The organization has already been addressed as one of the most innovative pharmaceutical organizations across the world. All this has been possible for the implementation of the OIDD program thatallowedthemanagementof EliLilly’sto ensure huge scaleresearchand development. 3.What challenges did Eli Lilly face in adoptingthe open innovation model? Explore the main challenges that the firm faced or may have faced in managing the OIDD platform andwhat solutions would you have proposed to overcome them.
6MEDICAL While the huge pool of information has been highly beneficial for the Elli Lilly organization and has resulted in huge success over time, the fact that a good number of challenges has also been faced by the organization while conducting the OIDD program cannot be ignored. According to researchers,thefivemostcommonchallengesassociatedwithopeninnovationincludes strategic, operational, legal as well as culture challenges. When it comes to strategic challenge the chief issue with the OIDD approach taken by the Elli Lilly organization includes the complexity of fully understanding as well as assessing compound differentiation along with including with greater resolution the possible mechanism associated with the action (Eckhardt et al. 2018). Fortunately, for the organization, this complexity has got substantiallyreducedafterthedevelopmentofadvancedassaytechnologiesalongwith informatics tools which make the challenges highly tractable for the drug discovery. Another major strategic challenge that may have been faced by the Elli Lilly organization is high rate of dependence of the organization on external resources. Considering the fact that a good number of researchers from all over the world have submitted their data that has been widely used by the company to develop effective medicines, there is a possibility that the company may develop high dependency on the same. According to researchers, lack of capability to innovate internally often result in enhanced reliance on external resources (Gascó 2017). A good number of organizations are found to be treating open innovation as an entirely separate unit. In order to deal with the issue of enhancement of dependency on the external researchers, one of the chief actions that can be taken by the organization is to treating both internal as well as external sources of information as a single unit. Not only this, in order to enhanced the capabilities of the researchers who work for the organization, the management should also
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7MEDICAL implement effective strategies so that a strong and effective internal source of information can be assured. Another major research issue that can be faced by the Elli Lilly organisation while conducting the OIDD program is lack of clear vision. Considering the fact that a good number of proposed structure are submitted by researchers across different parts of the world, analysing all the submission and creating a detailed report of the same is not only time consuming but also can impose negative impact on the investment cost of the organization (Gassmann et al. 2018). Not only this, this can also result is deviation of the organization from its goal. The fact that for including valuable ideas as well as knowledge from outside the organization, inevitable increment of both internal as well as external coordination cost as well as risk also needs to be faced by the organization. Thus it can be clearly understood that the Elli Lilly Company also had to invest a huge amount of financial resources in order to obtain external data from the organization. In the initial stage however, engaging external sources of collaboration for R&D maximizes the return while implemented minimal changes in the investment costs. With time, the changes of attracting a larger pool of potential talent for gathering promising ideas cannot be avoided. In order to prevent all these challenges from imposing adverse impact on the revenue of the organization, one of the major steps that can be taken by the organization includes shortlisting the proposed structure with the help of experts. Implementing this policy will not only enable the organization to save time as well as investment cost but also ensure that the target has been achieved with a shorter deadline. When it comes to operational challenges associated with open innovation, building an effective processisoftenfoundtobehinderedbychangeslikelackofstakeholder’ssupport, immeasurability as well as lack of strategic alignment (Gillespie et al. 2019). The fact that this
8MEDICAL issue may have been faced by the organization as well, effective strategies must be implemented by the organization to overcome these challenges. To make a process work it must be aligned with organizational goals as well as strategies and is communicated clearly to every individual involved in this issue. In order to ensure that the process is successful all the key stakeholders are engaged to the process. 4.What lessons can be learned from this case study? From the above case study it has been understood that the open innovation strategy possess the potential to enhance the degree of innovation that is needed for success of an organization.the open innovation strategy can be defined as the process of combining the internal resources with the external resources for boosting the innovative culture within an organisation.Some of the major advantages of implementing the open innovation theory in organization include innovation of old product or services, decrementsharing of R&D risks and costs, Faster R&D process and leveraging instruments. Open innovation enables the organization for sharing the risks as well as the costs of their Research and development processes (Santoro et al. 2018). Not only this, it and help the organization is by expediting their time to the market by acquiring valuable technology with the help of in licensing or a purchase of ownership rights rather than losing precious time in developing its own substituent of technology. It also creates an efficient pool of possibly for influencing the state of the market along with the behaviour of other predominant factors in the commercial environment. From the above case study we have understood the efficiency of the Open innovation Drug Discovery(OIDD)platformthathasbeenlaunchedbyahighlypopularAmerican pharmaceutical organization named “Elli Lilly and Company”. The mentioned platform has been designed for tackling different types of barriers that comes in the way of innovation with the help
9MEDICAL of identification of novel molecules that are active in relevant disease biological molecules. The OIDDprogrampossessthepotentialtoestablisheffectivecollaborationbetweenthe organization’s researcher and external researcher for accessing the novel chemical diversity that are present in individual research laboratories across the world (West and Bogers 2017). With the help of providing a secure platform that possess the potential to protect intellectual property, the OIDD program is found to be lowering the barrier associated with collaboration between the researchers who are working in different organizations.Lilly’s OIDD platform has brought about great success the world of pharmaceuticals. From the case study it can be clearly understood that developing the unique concept of creating an OIDD platform has resulted in huge success of the company (Spender et al. 2017). Access to a large pool of information has helped the organization to develop medicines more rapidly than its competitors. Thus, it can be understood that incorporating innovation results in enhancing competitive advantage, reputation and revenue of the organization. Along with this, from the case study, we have also learned the possible challenges that can be faced by an organisation while it implements the open innovation strategy.According to researchers, the five most common challenges associated with open innovation include strategic, operational, legal as well as culture challenges.One of the chief challenges includesstrategic, operational, legal as well as culture challenges. One of the chief strategic challenges faced by the Elli Lilly organization includes the complexity of fully understanding as well as assessing compound differentiation along with including with greater resolution the possible mechanism associated with the action (Wells et al. 2016). Another major strategic challenge that may have been faced by the Elli Lilly organization is high rate of dependence of the organization on external resources.In order to deal with the challenges, enhancing the potential of internal
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10MEDICAL information sources while opting from external sources of information has been suggested. However, till now the Elli Lilly organization have successfully overcome the challenges and have fostered efficiently in the healthcare university. In a nutshell, I understood that open innovation is highly crucial for each and every organization since it possess the potential to enhance competitive advantage of an organization which is a highly rare asset. Conclusion From the above discussion, it can be clearly understood that the open innovation strategy possess the potential to enhance the revenue of an organization by enhancing its reputation in the industry along with competitive advantage. In this world of high technical advantage, lack of informationalresourcescanslowdowntheresearchanddevelopmentcapabilityofan organization resulting in deterioration of its market value. In order to deal with this, the Elli Lilly Company has implemented the OIDD program that enhances the potential of the organization to enhance its innovative skills by allowing external researchers to submitting their research within the organization.However, a good number of changes has also been faced by the organization. To make a process work, it should be aligned with organizational goals and strategy and communicated clearly to everyone involved. In order to implement an effective open innovation strategy, it can be pointed out organizations needs to detect the challenges that can be faced by them along with implementing effective initiative to deal with the same.
11MEDICAL References Bogers, M., Chesbrough, H. and Moedas, C., 2018. Open innovation: research, practices, and policies.California management review,60(2), pp.5-16. Bogers, M., Zobel, A.K., Afuah, A., Almirall, E., Brunswicker, S., Dahlander, L., Frederiksen, L., Gawer, A., Gruber, M., Haefliger, S. and Hagedoorn, J., 2017. The open innovation research landscape:Establishedperspectivesandemergingthemesacrossdifferentlevelsof analysis.Industry and Innovation,24(1), pp.8-40. Carroll,G.P.,Srivastava,S.,Volini,A.S.,Piñeiro-Núñez,M.M.andVetman,T.,2017. Measuringtheeffectivenessandimpactofanopeninnovationplatform.Drugdiscovery today,22(5), pp.776-785. Chesbrough, H., 2017. The future of open innovation: The future of open innovation is more extensive, more collaborative, and more engaged with a wider variety of participants.Research- Technology Management,60(1), pp.35-38. Chesbrough, H., Lettl, C. and Ritter, T., 2018. Value creation and value capture in open innovation.Journal of Product Innovation Management,35(6), pp.930-938. Eckhardt, J.T., Ciuchta, M.P. and Carpenter, M., 2018. Open innovation, information, and entrepreneurship within platform ecosystems.Strategic entrepreneurship journal,12(3), pp.369- 391. Gascó, M., 2017. Living labs: Implementing open innovation in the public sector.Government Information Quarterly,34(1), pp.90-98.
12MEDICAL Gassmann, O., Schuhmacher, A., von Zedtwitz, M. and Reepmeyer, G., 2018. The open innovation challenge: how to partner for innovation. InLeading Pharmaceutical Innovation(pp. 111-133). Springer, Cham. Gillespie, J.J., Privitera, G.J. and Gaspero, J., 2019. Biopharmaceutical Entrepreneurship, Open Innovation, and the Knowledge Economy.Journal of Innovation Management,7(2), pp.59-77. Santoro, G., Vrontis, D., Thrassou, A. and Dezi, L., 2018. The Internet of Things: Building a knowledgemanagementsystemforopeninnovationandknowledgemanagement capacity.Technological Forecasting and Social Change,136, pp.347-354. Spender, J.C., Corvello, V., Grimaldi, M. and Rippa, P., 2017. Startups and open innovation: a review of the literature.European Journal of Innovation Management. Wells, T.N., Willis, P., Burrows, J.N. and van Huijsduijnen, R.H., 2016. Open data in drug discovery and development: lessons from malaria.Nature Reviews Drug Discovery,15(10), p.661. West,J.andBogers,M.,2017.Openinnovation:currentstatusandresearch opportunities.Innovation,19(1), pp.43-50.