This comprehensive guide explores the concepts of innovation and commercialization, examining their importance in organizational success. It delves into the 4Ps of innovation, frugal innovation, and the innovation funnel, providing practical examples and analysis. The guide also covers the commercialization process, including the commercial funnel and new product development (NPD), and explores methods for building innovation business cases and accessing funding. Additionally, it examines tools for developing, retaining, and protecting knowledge and intellectual property, offering evidence-based evaluations of their effectiveness in the wider business environment.