The Impact of Brain Lobe Lesions on Human Function
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This report discusses the main four lobes of the brain (frontal, parietal, temporal, and occipital) and their respective structures and functions. The impact of lesions to these lobes is explored, including difficulties in vision, movement, and locating objects. The report also references various studies and sources on the topic.
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Discuss the roles of each of the brain’s 4 lobes. Outline their key structures and their functionality. What are the possible effects of lesions to each of them?
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Table of Contents INTRODUCTION...........................................................................................................................1 MAIN BODY...................................................................................................................................1 CONCLUSION................................................................................................................................5 REFERENCES................................................................................................................................6
INTRODUCTION Brain refers to an organ composed of abigmass of nerve tissuewhichis secured within the skull. It has severalrolessuch asregulation of breathing & blood pressure, processing sensory data andreleasing hormones. However, brainis separated into several relevant lobes like parietal, temporal, occipital and frontal lobe.This presentedreport will focus on lobes of brain with their key structures as well as functionality. It will also include possible effects of lesions on these lobes of brain. MAIN BODY Brain can be described as one of the largest and most complex organs in human body. It is known as central organ of human nervous system and it consist several parts including cerebrum, brainstem and cerebellum. Meanwhile, brain is responsible for consisting four lobes that can be categorised into frontal, parietal, occipital and temporal lobes. Initially, frontal lobe is known as essential for regulating cognitive functions and controlling voluntary activity or movement of human body. However, parietal lobe is responsible to process data related to taste, touch, movement and temperature whereas occipital has function to regulate vision. Moreover, the processing of memories, integrating them through sensations of sound, sight, taste and touch. Frontal lobecomprise2/3rdof human brain and it is composed to two paired lobes of cerebral cortex including left & right frontal cortex. This lobe issituatedclose toforemostof head,belowthe frontal skull bonesas well asnearby forehead. However, it has been analysed that left frontal lobes are responsible for affecting muscles on right side of the body whereas right side of frontal lobe is controlling left part of human body. Moreover, there are several functions which are regulating by frontal lobe of brain in which its key role is planning of future that consist self management and decision making respectively. Hence, number of other roles of frontal lobe are explained here. Initially, Broca's region of frontal lobe helps to convert thoughts into words that results into ability of a person of speech and language creation. It is also helpful to few of motor skills like running and walking along with classifying objects to compare and distinguish them from one another. Basically, it has a key role of forming long term memories and understanding to feelings expressed by others to react for the same in suitable manner. It also consist the role of forming personality which is a complicated interplay of memory, impulse control and other tasks 1
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in order to formulate key characteristics of an individual. In addition to this, frontal lobe is responsibleforconsistingdopaminesensitiveneuronsofbrainwhichisachemicalfor supporting reward seeking behaviour as well as motivation. Moreover, it plays an important role to manage attention including selecting attention in different situations. Impacts oflesions to frontal lobeconsist altering personality of an individual and create issue like Attention-deficit/hyperactivity disorder (ADHD). If frontal lobe get damaged thena person often struggle to gather data, remember previous experiences and make decisions accordingly. Meanwhile, lesions on frontal lobe results into several symptoms such as falling, weakness, inability to problem solving, impaired judgement, decreased creativeness, reduced sense of smell or taste, depression, low encouragement, decreased sexual interest, low attention span and impulsive or risky behaviour. Moreover, number of mental health problems cause by damage in frontal lobe that includes dementia, stroke & transient ischaemic attacks, cerebral palsy, Huntington's disease, brain tumours, infections, Parkinson's disease, traumatic injury and Alzheimer's disease. Additionally, these the problems can be generated as an impact of lesions on frontal lobe of brain and requires immediatemedicationsfor maintaining appropriate psychological health of a person. Parietal lobeis superior to an occipital lobe and posterior to the frontal lobe & central sulcus in brain. It sits directly over the skulls hence it is known as parietal lobe of brain. The key role of parietal lobe is to interpret sensory information like letting a person know about location of body parts and aiding into physical navigation. However, there are number of functions which are regulating by parietal lobes of brain that are described here. Basically, parietal lobes consist somatosensory cortex within them which is responsible to help for determining location of touch sensation and differentiate among different sensations including pain and temperature. This lobe contains neurons that receive information related to vision, touch and another sensations from thalamus. It is also helpful for processing specific information in order to identify specific object by touching the same. Meanwhile, it has been analysed that parietal lobes perform with other parts of brains including motor and visual cortex in respect of performing certain tasks properly. Parietal lobe plays an important roleto make an individual capable to determine the location, position and movement of human bodyalong with its various parts respectively. It consist number of functions such asspeech, cognition, visual perception, writing & reading, mathematical computation, touch sensation (temperature, pain, etc.), movement coordination, 2
information processing and understanding spatial orientation. Meanwhile, it has key function of processing sensory information related to temperature and taste along with touching sensations in human beings. It is not possible for humans to feel anything about sensations if parietal lobe get damaged in any manner. For example, a person can only feel about location of their tongue due to proper working of this lobe and it helps to avoid biting it while chewing the food. Lesions occurring on parietal lobeare responsible for several symptoms and create problem for an individual. Initially, it effects the main functions of parietal lobe which indicates certain signs including loss of sensations such touch or pain and weakening of language development that create problem of a person in daily life . In addition to this, lesions in parietal role is responsible for developing a situation of astereognosis in which an individual face inability to determine things placed in the hands (PARIETAL LOBES,2019). However, damage in right parietal lobe results into contralateral neglect thatmaydamagepersonalaidabilities and it canreason atroublein constructingbelongingsi.e. constructional apraxia. It also consist problem of anosagnosia including denial of deficits and drawing capability. Meanwhile, it has been analysed that left parietal lobe get damaged then it will facilitate occurrence of Gerstmann's Syndrome consisting right-left confusion, problem in mathematics (acalculia) and difficulty with writing (agraphia). It is also responsible for causing language issues that is called aphasia and disability to perceive objects normally i.e., agnosia. Temporal lobeislocated in largest section of brain in human body which is called as prosencephalon (fore brain). It is located ininferior towards frontal & parietal lobes and anterior to occipital in brain.This lobeplayskey role in auditory perception, language & speech production, organising sensory input and formation & association of memory. However, the structureoftemporallobesconsistlimbicsysteminvolvingamygdala,hippocampusand olfactory cortex that helps in regulating its functions (Fang,Wang and Jiang, 2016). Moreover, Fissure of Sylvius that is considered as a large deep groove whichis responsible for separating parietal and temporal lobes. Temporal lobes consistmiddle, inferior and superior temporal convolutions andsidelongoccipitotemporal convolutions. It also includes fusiform, lingual and parahippocampal & hippocampal convolutions along with transverse gyri of Heschl that is known as primary auditory receptive area of brain. The connection of temporal lobes involves several pathways including hierarchical sensory, dorsal auditory, polymodal & medial (mesial) temporal pathway along with frontal lobe projection. 3
The mainfunctions of temporal lobesconsist number of aspects such asspeech, language comprehension, emotional responses, visual perception, facial recognition, memory and auditory perception.Thekeytemporal lobes has certain functions thatare related to hearing, memory and speech. Initially, amygdala is responsible for controlling several fear related autonomic responses, fight or flight response and generate proper sense of fear via fear conditioning. This part of temporal lobe collectdatafrom thalamus&another section of cerebral cortextorespondinanappropriateway.However,hippocampushasafunctiontoaid formulation of memory and link the emotions & senses including smell as well as sound. It has been analysed the Wernicke's area of brain isfoundedin temporal lobes which supports to process words along with understanding spoken language. It has a function of processing auditory information from ears in context of hearing properly. Lesions of the temporal loberesponsible for various problem such as change in behaviour & emotions, language & speech issues, difficultly in context of vision, forgetfulness, disable to concentrate and disruption in sense. It is responsible for disturbance in auditory sensation & perception, difficulty in music & visual perception, disruption to select auditory & visual input and disable for utilising relevant knowledge. The damage in temporal lobe results into altered personality & affective behaviour, impaired long term memory and alter sexual activity. Impact of lesions encourage occurrence of several syndrome likeWernicke's aphasia, amusia, visual agnosia, homonymous upper quadrantanopia as well as alterationinmental testof visuallyobserved matter(Brain Lesions,2019). Moreover, othersyndromes related to temporal lobesconsistgustatory & olfactory hallucinations, dreamy states, behavioural & emotional changes, delirium, disturbance of time perception, Korsakoff amnesic defect, placidity & apathy, visual,auditoryandKluver-Bucysyndrome(hypermetamorphopsia,hyperorality, hypersexuality and blunted emotional reactivity). Damage of temporal lobes may cause severe health problems that requires medical attention immediately in order to take effective clinical actions for making an individual well being. Occipital lobeconsist bottom and back part of cortex which is responsible for regulating vision of an individual. It consist number of structures & neural tractsconsidering dorsomedial stream, the lateral geniculate bodies, lingula, Brodmann area 17 and ventral stream.However, these are located in posterior region of cerebral cortex and known as main centres of processing the vision. The occipital lobes containsvisual processing and cortexcentresexist in human brain 4
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of thebody. It consist visual cortex that is responsible foracquiringunprocessedsensorydata with the help of sensors in retina of eyes that will transformed by optic tracts to the visual cortex. Functions of occipital lobeconsist various aspects including key role of regulating vision in human being. Initially, it is helpful in mapping the visual world that provide support in visual memory as well as spatial reasoning.However, it plays an important role to identify properties of colour relevant todifferent objectsexist invisualareaand facilitate inevaluating the size, distance as well as depth. In addition to this, it functions to facilitate determining visual stimuli specifically familiar faces and items and receiveunprocessedvisualinformationfrom perceptual sensors in retina of the eyes. Moreover, occipital lobe isaccountablefor transmitting visual data toward another section of brain so that thedesired functions can be carried out by brain lobes. Meanwhile, these functions includes assign meaning, craft motor & linguistic responses,encodememoriesandrespondtowarddataacquiredfromsurroundedworld continuously (Heilman,2016). Impact of lesions to occipital lobeconsist certain problems including epilepsy in which few of seizures take place and increase vulnerability to occurrence of the same. It consist the difficulties in movement face by an individual or if they can move then changes in depth perceptions and vision leads to improper movements as well as difficulty in navigating the visual field. Basically, they face problems in terms of perceiving various types of colours, shapes, dimensions and size. Meanwhile, the difficulty to recognise familiar objects or faces, read written words and hallucinations occurs (Occipital lobes,2019). However, damage to occipital lobe create disability of an individual to detect about movement of object, reading writing as words may appear to move on the page. Moreover, it can develop disruption in order to locate items within an atmosphere even when these objects are seen. Additionally, it is also creating difficulties with gross and fine motor abilities as well as balancing skills. CONCLUSION The above report has been concluded that brain has main four lobes such as frontal, parietal, temporal and occipital with their own structures and functions. It involves impacts of lesions creating difficulties in vision, movement and locate things in proper way. 5
REFERENCES Books and journals Baris, M. M. & et. al., (2016). Role of mass effect, tumor volume and peritumoral edema volume in the differential diagnosis of primary brain tumor and metastasis.Clinical neurology and neurosurgery.148.67-71. Fang, S., Wang, Y., & Jiang, T. (2016). The influence of frontal lobe tumors and surgical treatment on advanced cognitive functions.World neurosurgery.91.340-346. Heilman,K.M.(2016).Possiblebrainmechanismsofcreativity.ArchivesofClinical Neuropsychology.31(4). 285-296. Levan, A. & et. al., (2016). Right frontal pole cortical thickness and executive functioning in children with traumatic brain injury: the impact on social problems.Brain imaging and behavior.10(4). 1090-1095. Neulinger,K.&et.al.,(2016).Prospectivememoryandfrontallobefunction.Aging, Neuropsychology, and Cognition.23(2). 171-183. Online BrainLesions.(2019).[Online].Available through:<https://my.clevelandclinic.org/health/diseases/17839-brain-lesions> Frontallobe:Functions,structure,anddamage.(2019).[Online].Availablethrough: <https://www.medicalnewstoday.com/articles/318139.php> Occipitallobes.(2019).[Online].Availablethrough:<https://www.braininjury- explanation.com/consequences/impact-by-brain-area/the-occipital-lobe> PARIETALLOBES.(2019).[Online].Available through:<https://www.neuroskills.com/braininjury/parietal-lobes/> 6