Animal Testing in Medical Research: An Annotated Bibliography

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Nursing 2
Part 1: Annotated Bibliography
Does Animal Testing Still have a place in Medical Research
Franco, N. (2013). Animal experiments in biomedical research: a historical
perspective. Animals, 3(1), 238-273.
The article examines the present use of animal models in biomedical research based on history,
providing an understanding of the progressive development of the current regulations on animal
experimentation. The use of animal models in scientific research has made significant
contributions to the current development in medical research, however, this has been met with a
heated debate on whether it is reliable and ethical. The current situation requires an
understanding of the medical progression from a historical perspective. This article is critical for
the literature review because it provides more insight into the developments in the current
medical world and on the heated debate on animal testing. Furthermore, the article is important
in the nursing profession because it provides information on the contribution of animal testing to
biomedical research. The article was searched in the MDPI database using the following key
terms: biomedical research, animal testing, history of science
Mak, I. W., Evaniew, N., & Ghert, M. (2014). Lost in translation: animal models and clinical
trials in cancer treatment. American journal of translational research, 6(2), 114–118.
The authors were aimed at presenting the current state of animal model translation to clinical
practice and justify why the process has not been successful in cancer treatment. As much as
animal models have been used in cancer research, the success rate of the translation of the
outcomes from the animal model to clinical cancer trials has been relatively low. This is because
the safety and efficacy that is recognized in animal testing are not usually deciphered to human