2NURSING ASSIGNMENT Question 1 Medical cannabis or medicine marijuana is cannabis or cannabinoids which the doctors prescribe for the patients. The uses of the cannabis has not been tested much because of the Governmental restrictions. This has resulted in the limitations of research regarding to the safety and efficacy of using cannabis for treating diseases. The medicinal uses of cannabis are described below: The medical cannabis is somewhat very active in reducing nausea and vomiting induced by chemotherapy. Cannabis is effective in freeing from chronic pain in several conditions. It is also reported that cannabis can also treat peripheral neuropathy. It is also very effective in treating chronic problems like multiple sclerosis and problems involving movement (Abuhasira, Shbiro & Landschaft, 2018). Question 2 The pharmacokinetics of cannabis includes hoe the medicine is absorbed in the body through different modes of administration and from different drug formulations. This involved how the drug is distributed in the body, the metabolism and the way the drug are excreted from the body. The bioavailability of this medicine given directly intravenous I s100%. He other forms of taking of cannabis includes smoking, application to skin and eating, which gives less bioavailability. The metabolites are mainly found in the plasma factors of blood in which 95-99% of them are bound to the lipoproteins. In the erythrocyte only 10% of these cannabis are found, the concentrations of cannabis on the blood is only one and a half concentration of the specimens of
3NURSING ASSIGNMENT blood plasma. The concentration of Tetrahydrocannabinol (THC) decreases rapidly because of the rapid distribution in the tissues and liver metabolism. Most of the THC which enters into the body are metabolized in the liver into 100 or more metabolites. The primary metabolite are psychoactive and the effects of these are very rapid. The metabolized part of these materials are inactive which get excreted out through faces and urine (Newmeyer et al., 2016). Question 3 Tetrahydrocannabinol (THC) is the most important source of pharmacologic effects caused mainly by the effects of the consuming cannabis. If the drug crosses the psychotropic threshold, the taking of cannabis enhances the well-being of the person. The most important effect of caused by the over dosing of cannabis are anxiety and panic attack. Pharmacodynamic interactions can occur if the drug is administered through orally along with other drugs of central nervous system. Cardiac toxicitycan occur through the increased hypertension along with tachycardia with sympathomimetic agents. Not much information about the pharmacodynamics are available for this medicine (Badowski, 2017). Question 4 The risk factors which are required to be considered during the assessments of patients are: The personal history of the family history of the person are required to be considered that whether they have any issues of bipolar disorder or psychosis or not. The frequency of the medicine must also be checked. The type of the product must be taken into consideration.
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4NURSING ASSIGNMENT The age of the person must be taken into consideration as the risk are associated mostly with the age of the person. The circumstances of use, like whether other mediators are combined with the drug or not. The method of use is another important factor as smoking of cannabis is the most risky method than other methods of administration (Shakoor et al., 2015).
5NURSING ASSIGNMENT References Abuhasira, R., Shbiro, L., & Landschaft, Y. (2018). Medical use of cannabis and cannabinoids containing products–Regulations in Europe and North America.European journal of internal medicine,49, 2-6. Badowski, M. E. (2017). A review of oral cannabinoids and medical marijuana for the treatment of chemotherapy-induced nausea and vomiting: a focus on pharmacokinetic variability and pharmacodynamics.Cancer chemotherapy and pharmacology,80(3), 441-449. Newmeyer, M. N., Swortwood, M. J., Barnes, A. J., Abulseoud, O. A., Scheidweiler, K. B., & Huestis,M.A.(2016).Freeandglucuronidewholebloodcannabinoids' pharmacokinetics after controlled smoked, vaporized, and oral cannabis administration in frequent and occasional cannabis users: identification of recent cannabis intake.Clinical chemistry,62(12), 1579-1592. Shakoor, S., Zavos, H. M., McGuire, P., Cardno, A. G., Freeman, D., & Ronald, A. (2015). Psychotic experiences are linked to cannabis use in adolescents in the community because of common underlying environmental risk factors.Psychiatry research,227(2- 3), 144-151.