This nursing case study focuses on Type 2 Diabetes Mellitus and explores various treatment options, pathophysiology, complications, and medication. It provides expert guidance on nursing considerations and patient indicators.
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Contents INTRODUCTION...........................................................................................................................1 Part 1................................................................................................................................................1 1.1................................................................................................................................................1 1.2................................................................................................................................................2 1.3................................................................................................................................................2 Part 2................................................................................................................................................3 2.1................................................................................................................................................3 2.2................................................................................................................................................5 Part 3................................................................................................................................................6 3.1................................................................................................................................................6 CONCLUSION................................................................................................................................7 REFERENCES................................................................................................................................8
INTRODUCTION A case study based on Emily Smith will be analysed in this report who is suffering from Type 2 Diabetes Mellitus. In this report various treatment options of T2DM will be analysed along with surgical options to the patients. The main aim of developing this report is to enhance the nursing decision making. Part 1 1.1 The case study of Emily Smith is focused towards the Type 2 Diabetes Mellitus which has been diagnosed 6 months ago. At this stage, it is possible to control this Diabetes condition. The concept of pathophysiology is a study in which it can be identified that how a disease can affect the systems of a body. Pathophysiology for Type 2 Diabetes Mellitus in this case Insulin resistance and decreased insulin secretion. Insulin resistance is a pathophysiology which is a result of T2DM in this case of Emily Smith. Insulin resistance is a condition where when insulin is injected in the body, it fails to exert sufficient action in respect to the blood concentration(Zheng, Ley and Hu, 2018). In simpler words, insulin resistance is what limits insulin to act in a human body. This condition further targets main organs of a human body that can include liver. For this pathophysiology, it is important to analyse how insulin actually works. The insulin has the ability to limits the production of glucose in a human body which ensures the efficient functioning of liver and other muscles but the T2DM builds a resistance in human body for insulin due to liver organ is at risk. Another pathophysiology for T2DM is impaired insulin secretion; in this pathophysiology responsiveness of glucose decreases due to which human body develops glucose toxicity. Type 2 Diabetes Mellitus is a common condition which has various risk factors including overweight, inactivity of patient, medical history of patient, medical history of patient’s family, distribution of fat and age(Zeitler and et.al., 2018). All these factors can increase the risk of T2DM. All these risk factors will levy 90% chances for a human to adopt this disease. The most influential risk factor is over weight as being overweight can old can elevate the chances of suffering from this medical condition. It is important to understand the pathogenesis of Type 2 Diabetes Mellitus and this can be understood by analysing the source of this disease that can be genetic and acquired. The 1
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pathogenesis of Type 2 Diabetes Mellitus includes beta cell dysfunction and insulin resistance. A beta cell dysfunction includes both acquired and inherited factors and it has been also observed that ethnic groups can even have a marked difference. It is important to identify possible complications under Type 2 Diabetes Mellitus so that case of Emily Smith can be analysed with appropriate medical treated. The complications under T2DM includes kidney damage, slow healing, nerve damage, heart and blood vessel disease. These complications will result due to insulin resistance will has lead towards the elevated glucose in the body. There are three levels of a treatment which are referred as primary, secondary and tertiary. Three levels of treatment options for T2DM includes physical exercise, weight loss and healthy eating; this treatment is the primary treatment for this disease(Kato and et.al., 2019). Secondary treatment of this disease is insulin therapy along with regular blood sugar tests and tertiary treatmentofthisdiseaseincludesinhibitors,receptors,metformin,sulfonylureasand meglitinides. The above treatment can Emily Smith to control her Type 2 Diabetes Mellitus. It is also required in her case that all risk factors are identified as according to her this disease is common in her family medical history. 1.2 Differences in T2DM and T1DM includes the following: T1DM or type 1 Diabetes Mellitus is a condition where cells in a human body’s pancreas are attacked due to which body unable to make any insulin. On the other hand, Type 2 Diabetes Mellitus or T2DM, body becomes unable to make enough insulin to fight blood sugar. Another difference between these diseases is T1DM’s symptoms appear quickly and symptoms of T2DM takes time to appear. T1DM can be controlled by treating with insulin and T2DM demands combination of medication and physical diet and exercise. T1DM is usually diagnosed in childhood but T2DM is diagnosed in older adults. T1DM is a condition which is associated with higher ketone levels and T2DM is associated with hypertension and high cholesterol levels(Jalal and et.al., 2017). 1.3 On admission, blood glucose level of Emily Smith was 22.9 mmol/L [3.9-6.1 mmol/L] which quite high when fasting. There are two reasons which are identified that can justify being 2
the cause of high glucose level. The first reason is stress; Emily was devastated when she came to know that she is suffering with the condition of T2DM. Although Emily fo not have any medical history indicating towards T2DM, but Emily family medical history is known to have this condition as her mother and elder sister had this condition at their early 50s. Considering this, it can be said that stress is the major cause of Emily’s elevated blood glucose level. The cause “stress” impact blood glucose level; when a human body experiences stress, the adrenal glands present in the body triggers the release of glucose which is already stored in certain organs of the body and by this glucose level is increased in body(Orno, Arif and Idris, 2018). Another cause due to blood glucose level of Emily was increased on admission was her inability to perform regular physical exercise. Along with T2DM, Emily was also having an issue of Bakers Cyst that needed to be drained. Such Bakers Cyst is a condition in which a cyst containing fluid is grown behind the knee which results into pain and problems in walking. Due to facing issues while walking, Emily was unable to walk properly and perform exercise and this elevated her blood glucose level. The cause “Lack of regular exercise and overweight” impacts blood glucose level; when bod mass index of a patient increases the insulin resistance also increases which results in high glucose level in body. Part 2 2.1 MedicationDiscussionActionComplications/side effects Nursing considerations Cortisone injections (Kenacort- A 40) Emily Smith was giventhis medicationfor herpostsurgery nursing.This medication is for systematic corticosteroid therapy which can eliminate the risk An action refers to theactionof medication which it performsina humanbody. Kenacort-A40 actions to suppress inflammationin skin and eliminates swelling and helps This medication is used in form of an injectionandcan resultinmultiple side effects which includesjoint pains,infection and in some cases headache.This medicationcan Whileinjecting Kenacort-A 40, it is importantto considered that this medicine is injected deepintothe musclesothatit canbeabsorbed intobloodrather thanintoskinas 3
ofpostsurgical issuesincluding allergiesand tissue disorders. inreducingpain. Thismedicationis forEmily’spost surgery which will help in reducing the joint problem at her knee. evenreactwith partoftheskin whereinjection needle is injected. skin acts as a carrier to supply medicine to all parts of the body(Webster and et.al., 2017). Metformin (APO- Metformin Tablets) Metforminisa medicine which is giventoEmily Smithtocontrol her glucose level and to make sure thathertype2 diabetes is under control.This medicinecanbe given to adults as wellasto children who are above 10 years. Thismedicineis part of a medicine groupwhichis calledbiguanides. When this medicine isconsumedbya patient it triggers to lowerdownblood glucoselevelin body by helping the body to make better use of insulin which is produced by the pancreas. Therearevarious side effects of this medicine but none ofthemisat chronic level. The side effects of this medicineincludes diarrhoea, dizziness, weakness, vomiting, irregular heartbeats,cold andpainin muscleswhichis reportedas unusual. Thismedicineis observedtobe appropriatefor patients like Emily whoare overweight.Itis importantto considersome nursing considerations beforeconsuming this medicine. Such considerations includestorageof this medicine in an airtightcontainer in a cold place and ensuring patient do notusethis medicineifhave renal problems even suchproblemsare mild. GlipizideThismedicineisThismedicineisSide effects of thisThismedicinehas 4
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(Minidiab Tablets) given to Emily to control her blood sugar.This medicineisused inconditions wherepatients requires mediationtoact non dependent on insulin.This medicineis differentfrom abovemedicine ofT2DMasit actsasan additionto regularexercise and healthy diet. dissolved blood of a humanbodyand lowerdownsthe bloodglucoseby elevatingthe amountofinsulin whichisproduced by pancreas. medicineare similarto Metformin.Few distinctiveside effectsinclude nausea,lossof appetite,weight gain and headache. fewnursing considerationsas wellwhichstate this medicine must notbegivento patientswhichhas medicalhistoryof beingallergicto sulfonylureasand pregnancy (Romagnaniand et.al., 2017). 2.2 BGL or blood glucose level is the level of glucose in a human body. This level was 22.9 mmol/L [3.9-6.1 mmol/L] at the time of Emily’s admission to the hospital before surgery. This level decreased to 8.8 mmol/L [3.9-6.1 mmol/L] when Emily came to the outpatient clinic. The BGL measures the level of glucose and sugar content in the blood of a human body. A BGL of less than 7.8 mm0l/L is considered as normal but at both the times BGL of Emily was higher than this rate indicating Emily was suffering and is suffering from type 2 diabetes. The blood glucose level of Emily changes for various reasons. These reasons include stress and medication; when Emily was admitted for surgery, she was stressed due to which her BGL was higher and then lowered down at the time of her check-up. Also, Emily was given medicines such as Metformin and Glipizide which decreases her BGL. 5
HbA1c or Glycated haemoglobin is a type of haemoglobin which is linked to sugar. The time of admission of Emily at hospital, her HbA1c was 11% [normal <6.5%] and later it changed to 8% [normal <6.5%]. A HbA1c measures the level of haemoglobin in a human body which is linked with sugar and a normal HbA1c is 6.5%. This level has changed due to proper medication intake by Emily. Part 3 3.1 A renal function test is conducted to examine the blood urea nitrogen to determine effectiveness of the kidney functioning. The renal function test of Emily indicates that her GFR (glomerular filtration rate) is 10ml/min/1.73m2. When GFR is less than 15ml/min/1.73m2, it is said that patient has G5 category. A G5 category refers to the end stage of renal failure and it represents that Emily has lowest level of kidney function. As the Hb (Haemoglobin) of Emily Smith was 95g/L, it indicates that Emily has kidney problems, gastrointestinal blood loss and none marrow suppression(Kalantar-Zadeh and Fouque, 2017). Another indicator is serum potassium; the Serum Potassium of Emily is 5.7 mmol/L which is higher than normal limit [3.6 to 5.2 mmol/L] and this indicates kidney failure and hypoaldosteronism and this is the reason due to which Emily is experiencing palpitations. Serun Urea 17 mmol/L is another indicator which indicates that Emily Smith has higher Serum Urea as normal limit for this test of Emily must be [2.9-8.2 mmol/L]. This elevated limit indicates congestive heart failure and heart attack. Last indicator from renal function test of Emily is Serum Creatinine 150 μmol/L which is quite as normal limit is [50-110 μmol/L]. A higher Serum Creatinine indicates that kidneys are not working well(Liu and et.al., 2018). As per the indicators above, it is clear that Emily is suffering from chronic kidney disease. There are two treatments available for Emily which are medicine for high blood sugar and glucose and dialysis(Drawz, Hostetter and Rosenberg, 2020). The rationale for suggesting medicine as treatment is that it will cure the cause of CKD which is high blood sugar. The rationale of suggesting dialysis is that it will replicate some of the kidney’s function which are necessary in stage 5 CKD. 6
CONCLUSION From the above report, it has been concluded that it is important to understand the medical history as well as immediate family’s medical history to ascertain the cause of a disease. It is also concluded that a case may represent disease causes as hereditary or adapted. 7
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REFERENCES Books and Journals Drawz, P., Hostetter, T. H., & Rosenberg, M. E. (2020). Slowing progression of chronic kidney disease. InChronic Renal Disease(pp. 937-959). Academic Press. Jalal,M.&et.al.(2017).AssociationofNonalcoholicFattyLiverDiseasewithInsulin Resistance in Type 2 Diabetes Mellitus–A Prospective Study.J Fam Med.4(4). 1119. Kalantar-Zadeh,K.,&Fouque,D.(2017).Nutritionalmanagementofchronickidney disease.New England Journal of Medicine.377(18). 1765-1776. Kato, E. T. & et.al. (2019). Effect of dapagliflozin on heart failure and mortality in type 2 diabetes mellitus.Circulation.139(22). 2528-2536. Liu,B. C.&et.al.(2018).Renaltubuleinjury:adrivingforcetowardchronickidney disease.Kidney international.93(3). 568-579. Orno, T. G., Arif, M., & Idris, I. (2018). Correlation Between Onset of Diabetes Mellitus and Nitric Oxide Levels in Patient with Type 2 Diabetes Mellitus.Medical Laboratory Technology Journal.4(1). 8-11. Romagnani, P. & et.al. (2017). Chronic kidney disease.Nature reviews Disease primers.3(1). 1- 24. Webster, A. C. & et.al. (2017). Chronic kidney disease.The lancet.389(10075). 1238-1252. Zeitler, P. & et.al. (2018). ISPAD clinical practice consensus guidelines 2018: type 2 diabetes mellitus in youth.Pediatric diabetes.19.28-46. Zheng, Y., Ley, S. H., & Hu, F. B. (2018). Global aetiology and epidemiology of type 2 diabetes mellitus and its complications.Nature Reviews Endocrinology.14(2). 88. 8