This article discusses the laws, ethics and professionalism in nursing practice. It explains the values and characteristics of professionalism that contribute to health care through collaboration, cooperation and therapeutic communication. It also covers the key principles implicating the legal, ethical and professional course of action and codes that corroborate the practice of registered nurses in Australia. The article also highlights the importance of evidence-based practice in nursing and the NMBA competency standards, codes of ethics and practice for the registered nurses.