Parkinson’s Disease And Dopamine Agonist

Running head: PARKINSON’S DISEASE AND DOPAMINE AGONIST
Parkinson’s disease and Dopamine Agonist
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PARKINSON’S DISEASE AND DOPAMINE AGONIST
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Abstract
Introduction
The cases of Parkinson’s disease are enhancing 1 per 100 populations among the age group
of 60 years or more. Parkinson’s disease is a brain disorder that is characterized by the
presence of shaking, altered balance, stiffness, difficulty in walking. The patient may
experience mental and behavioural changes, sleeping problems, fatigue, depression,
difficulties in memory as well. This section is designed for the peers of the neurology wards
of the hospital care setting.
Discussion
The disease is characterized by primary motor symptoms and secondary motor symptoms.
The patients may experience shaking of hands, legs, arms, tongue, lips, jaws, rigidity of
muscles, joint pains and muscles. Moreover, cases of bradykinesia are also reported and as a
part of this, problems like reduced facial expression, lower rate of eye blinking, reduction in
the quality of hand writing due to shaky hand are observed. . Among the secondary motor
symptoms the main features are tendency to bend forward, impaired gross and fine motor
responses, dystonia, fatigue, akathisia, cramping, sexual dysfunction, drooling and problem
in chewing and swallowing of the foods. The main reason of this disease is associated with
the destruction of DA-neurons of SNpc and along with this accumulation of tau protein or
neurofibrillary tangles (NFT) can also promote onset of the disease. For managing the disease
condition, dopamine agonist such as Ropinirole can be used.

PARKINSON’S DISEASE AND DOPAMINE AGONIST
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Conclusion
Therefore, it can be concluded that the low level of dopamine in PD is due to DA neuron
degeneration and accumulation of NFT. In order to prevent this dopamine agonists can be
prescribed.

PARKINSON’S DISEASE AND DOPAMINE AGONIST
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Introduction
Around the world, a huge number of patients are suffering from a neurological
disorder named Parkinson’s disease and in case of Australia the condition is not all different.
In this context, it is very crucial to mention the fact that almost 4 out of 1000 people in
Australia are suffering from this disease condition. Along with this, it is also reported that the
cases of Parkinson’s disease are enhancing 1 per 100 populations among the age group of 60
years or more. Therefore, almost 80,000 people in the country is living with this problem and
only one out of five disease cases are diagnosed before the age of 50 years
(Betterhealth.vic.gov.au, 2020).
What is Parkinson’s Disease
As per the information of National Institute on Aging, it can be stated that the
Parkinson’s disease is a brain disorder that is characterized by the presence of shaking,
altered balance, stiffness, difficulty in walking. Therefore, it is observed that along with the
advancement of time, the symptoms and condition of the disease generally get worse.
Moreover, along with the progression of the disease, the patient may experience mental and
behavioural changes, sleeping problems, fatigue, depression, difficulties in memory as well.
According to the study of Kouli, Torsney and Kuan (2018), it is stated that, the disease
affects both men and women; however, men are more affected by this disease condition than
that of a women. The study also stated that the advancement of age is a major risk factor for
developing this disease condition.
Physiology of Parkinson’s disease
While discussing about the physiology of PD, it can be stated that the disease is
characterized by a few features and they can be divided into two categories- primary motor