Globalization and digitalization make the work nature more dynamic and complex that causing the risk in the supply chain. This study material shows the contemporary issues that arise due to some external and internal factors and the role of lean and agile strategies to ensure resilience in the supply chain. Different secondary evidence from the research will address that what are the factors that cause disruptions in the supply chain and how its sustainability, product quality, and overall business performance can improve while integrating lean and agile approaches.