Table of Contents Article : Self Reported Sleep Duration, Sleep Quality and Breast Cancer Risk in a Population Based Case Control..........................................................................................................................1 1. Description...................................................................................................................................1 2. Article Critique...........................................................................................................................1 2.1 Title and Abstract.............................................................................................................1 2.2 Introduction......................................................................................................................2 2.3 Materials and Methods...............................................................................................................2 2.3.1 Settings and participants................................................................................................2 2.3.2 Study Design.................................................................................................................3 2.3.3 Statistical Methods........................................................................................................3 2.4 Results........................................................................................................................................3 2.5 Discussion and conclusion.........................................................................................................4 REFERENCES................................................................................................................................5
Article : Self Reported Sleep Duration, Sleep Quality and Breast Cancer Risk in a Population Based Case Control. 1. Description Article base on the study of Breast cancer and showing that it is one of the most common disease which diagnosed in invasive cancers. In other words, Several studies has found that lack of sleep cause risk of breast cancer. According to data In Australia and globally Breast cancer is the leading cancer found in Women. Present study is also stated the two biological models which has been proposed and explained how poor sleep can directly affect the development of cancer. Overall, the aimed of this study is to investigate the relationship between breasts cancer and 3 domains of sleep. Besides, this study also conducted a deep review of 1000 cases and 2000 age matched controls (Dini and et.al., 2018). Controls were women between the age group of 18- 80 living in Western Australia. All these participants were randomly selected from the electrol roll. Present paper is clearly makes the sense which is easy to understand the purpose of the study. 2. Article Critique 2.1 Title and Abstract Present study is effectively accomplish the aim of the study but could have been done more better if they adopt the tool of research critique checklist. Meanwhile, the purpose of Abstract is to provides the short and informative and balanced summary. The strength of the study is to conduct large population based case which significantly described the relationship between sleep durations on workdays and non workdays and including subjective sleep quality. In order to read the study, reader clearly get understand that what has been done throughout the research. Study also mentioned some keywords through everything is easily get understand like “Impaired Immune system”, “Metabolic pathways”, Obesity, Circadian rhythm, sleepetc (Monteiro and et.al., 2018). Present study is approved by the human research ethics committees of the Western Australian Department of Health and the University of Western Australian. Study alsoconductedsurveyandaskedtoparticipantstocompleteaselfadministeredpostal questionnaire that contained questions on demographic, reproductive and lifestyle factors or related to sleep. 1
2.2 Introduction Research consists most important part which is introduction. As same with this research, introduction of the study briefly explained the overview of Self reported sleep duration, quality of sleep and breasts cancer. From which it clearly stated that due to lack of quality sleep risk breasts cancer has been increased (Rashid and et.al., 2017). Introduction part also clearly mentioned the aim of the study is to examine the relationship between breast cancer and 3 domains of sleep. Also it explained the cases based on the issue alike cases were female residents in Australia. Introduction also described that major part of the study is based on hypothesis study. Study conducted survey on selection bias which is based on information on age, socio- economic status. Further to conduct a data analysis researcher has been taken selection bias and misclassification bias. Under which selection bias data is base on age, socio-economic status. Besides, misclassification bias is based on our exposure variables (Sharma and Singh, 2017). So the study wants to find that weather the sleep factor is playing a major role in breast cancer or not. Introduction is the significant part of the study which helps to elaborate the study into briefly manner and also explained the purposeful study to find out the results. 2.3 Materials and Methods 2.3.1 Settings and participants This study was conducted in Western Australia which was a case control study of environmental and occupational risk factors for breast cancer. In this research, researchers have used descriptive categories in order to describe the locations, setting as well as relevant dates. All of these categories has been fairly achieved by the research. The participants which where involved in the research were the female residents of Western Australia which were aged between 18 and 80 years. Also, the sample size of 1000 cases and 2000 ages matched control was calculated which was based on expected number as well as recruitment rate of breast cancer patients in Western Australia. The questionnaire which were filled by the participants had 95% of response from the participants. 5% of data was missing and another drawback of this research was misclassification bias which was manly due to exposure variables which where categorical. This research has achieved its aim of increase of risk of breast cancer which was expected to detect and for this Western Australia was chosen but it was not explained why this particular area was chosen. Also, Exclusion and inclusion criteria was discussed in the study, those cases where excluded if the cancer was not invasive which have increased the quality of research. 2
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2.3.2 Study Design The study design of this study was descriptive and logical which made it easy for readers to understand the measure which were taken in order to assess the disability and frailty of the chosen participants. In this research, frailty index was chosen but does not explain the reason behind it (Clark and et.al., 2016). There are various other frailty assessment tool which could have used like clinical frailty scale which determines person's level of frailty. One of the weakness of the study design was that the way that disease was reported, this research was based on there activities such as sleep duration, sleep quality and risk of breast cancer which could have created a bias while reporting the risk of breast cancer in females. But the major advantage of this research is that all three activities where well linked with each in order to provide appropriate results. 2.3.3 Statistical Methods Statistical analysis of this research was thoroughly describes and the method which was used for this research was polytomous regression modes were used in order to determine the odd ratios. In this report stratified analysis was also conducted for three characteristics of the circadian rhythm. The statistical methods which were used for this research have made it easier for researcher to replicate the study. The weakness of this study is that not a single reason was given why 1000 participants were selected for the researcher which where followed. Women which were selected for this research were aged between 18 and 80 years and were randomly selected by the researchers through electoral roll (Shokouh and et.al., 2017). The participants which were chose for the study have to complete self-administrated postal questionnaires on their reproductive, demographic as well as lifestyle factors in order to get proper results. Various statistical analysis which were conducted in this research by researchers is Stata 12 and Microsoft Excel 2010 which were the most tools used for statistical analysis. Also, all statistical test which were used in this research were two-sided which has increased the quality of the result and have make effective presentation of data. 2.4 Results Results of this research were presented in a proper systematic manner which has increased the quality of the research. There were different table used in order to present the results which were based on the replies from the participants. Each result of the research were describes the variables which are being measured and compared (Tucker Lima and et.al., 2017). 3
In the study use of tables were properly made which have made it easy to make proper comparison as well as associate the results with variables. This is also the strength of the research, but the weakness of the study the results where not presented in the graphical from. The results of the study was limited to primary objective of the research i.e. sleep duration, sleep quality and breast risk in a population. This research could have presented various other social determinants of health and their association with risk of breast cancer in females, the mortality, frailty and disability. This could be used by the researchers in their future study. 2.5 Discussion and conclusion From the above study it has been based on the topic Self reported sleep duration, quality of sleep and breasts cancer”. From the participation study of 2994 approximately 5% had missing data, leaving 2828 for sleep duration analysis and 2827 for sleep quality analysis. As per the results, it has been outlined that after conducting survey of sleep duration only 5% of respondents fell into the the last categories which is 8 hours. Limitation of the study is it demonstrate and focus on only sleep factor besides there are some more factors through which breast cancer is diagnosed (Valente and Pitts, 2017). Due to recall bias if the study it affects the results, since sleep is not widely recognized by the public as a possible risk for cancer. The aim of the study is not fully analysed that the cancer is diagnosed only due to sleep quality, sleep duration. Overall, the it has been analysed from the study that it does not provide evidence to support an association between self reported sleep duration lead a breasts cancer. So in order to recommend this study, it required to addressed and measure the epidemiologic in sleep. 4
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