Diabetes Mellitus and Associated Pharmacological Treatment
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Added on 2023/04/24
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This paper provides a summary of diabetes mellitus and its associated pharmacological treatment. It discusses the risk factors, potential medications, and two most common treatments - metformin and Rosiglitazone. The study is highly relevant to nursing practice and self-care management.
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Running head: ENDOCRINE DISEASE Name of the Student: Name of the University: Author note:
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Introduction: Over the decade, the predominance of diabetes mellitus type II affected a considerate number if individuals in Australia.It is diabetes mellitus is a group of metabolic disorder characterized by hyperglycemia which resulted from a defected secretion of insulin from the body (Forslund et al., 2015). This paper will provide a summary of the diabetes mellitus and associated pharmacological treatment. Discussion: Due to risk factors such as sedentary lifestyle, obesity, family history, Obesity, prediabetic symptoms,glucose level increased in the blood because ofglycogen metabolism andtheinsulin-producingbetacellsinthepancreasesstartedsecretingmoreinsulin’s. Consequently, cells become impaired to meet the demand of the body and Give rise to diabetes mellitus and affected other organs. Diabetes dramatically increases the risk of heart disease, diabetic retinopathy, and diabetic neuropathy (Rubino et al., 2016). The potential medications are Biguanides(metformin),Thiazolidinedione(Rosiglitazone),Alpha-glucosidaseinhibitors ( acarbose), Dopamine agonist), DPP-4 inhibitors. In the current context two most common and potential treatment are metformin and Rosiglitazone. Metformin is biguanide anti-hyperglycemic agentused for treating blood glucose level. It improves glycemic controls by decreasing hepatic glucose. On the other hand, it is anti-diabetic drug in the thiazolidinedione class of drugs (Courcoulas et al., 2015). It is administrated to the patient with type II diabetes mellitus in combination with metformin.The study is highly relevant to the nursing practice since it will also help nurses to provide safe and responsive care to the patient, support patient in self-care management.
Conclusion: Thus,itcanbeconcludedthatdiabetesmellitusisadisease,whichrequireboth pharmacological and non- pharmacological interventions. Crucial consideration in this case is exercise and dietary modifications which are required for leading a quality life.
References: Courcoulas, A. P., Belle, S. H., Neiberg, R. H., Pierson, S. K., Eagleton, J. K., Kalarchian, M. A., ... & Jakicic, J. M. (2015). Three-year outcomes of bariatric surgery vs lifestyle intervention for type 2 diabetes mellitus treatment: a randomized clinical trial.JAMA surgery,150(10), 931-940. Forslund, K., Hildebrand, F., Nielsen, T., Falony, G., Le Chatelier, E., Sunagawa, S., ... & Arumugam,M.(2015).Disentanglingtype2diabetesandmetformintreatment signatures in the human gut microbiota.Nature,528(7581), 262. Rubino, F., Nathan, D. M., Eckel, R. H., Schauer, P. R., Alberti, K. G. M., Zimmet, P. Z., ... & Amiel, S. A. (2016). Metabolic surgery in the treatment algorithm for type 2 diabetes: a joint statement by international diabetes organizations.Surgery for Obesity and Related Diseases,12(6), 1144-1162.