Applied Biostatistics Assignment

PUH 5302, Applied Biostatistics
Unit II Problem Solving Assignment
This assignment will allow you to demonstrate the following objectives:
 2.1 Compute the appropriate data to compare the extent of disease between groups.
 2.2 Summarize data collection in a sample.
Instructions: In this assignment, you will be applying the concepts of quantifying the extent of a disease
and summarizing data collected that you have learned in this unit. To complete this assignment, answer
the questions directly on this document. When you are finished, select “Save As,” and save the document
using this format: Student ID_Unit# (ex. 1234567_UnitI). Upload this document to Blackboard as a .doc,
docx, or .rtf file.
1. A study was devised to show the relationship between prevalent hypertension and prevalent cardio
vascular disease (CVD) in a heart study among a sample of 3986 participants. The following results were
obtained for prevalent hypertension and prevalent CVD.
No CVD Have CVD Total
No hypertension 2655 300 2955
Hypertension 750 281 1031
Total 3405 581 3986
Calculate the following and interpret your results:
a. Point prevalence of participants with CVD:
Point prevalence refers to the ratio of patients having the disease to the total
number of subjects studied.
The point prevalence of CVD
¿ HavingCVD
Total = 581
3986 =0.1458=14.58 %
b. Population attribution risk of participants:
Population attributable risk = P Poverall −P PUnexposed
P Poverall
=¿
P Poverall is equal to the point prevalence of CVD = 0.1458
P PUnexposed is equal to the point prevalence of persons having CVD with no hypertension
¿ 300
2955 =0.1015
Thus, population attributable risk ¿ 0.1458−0.1015
0.1458 = 0.0443
0.1458 =0.3038
Thus, 30.38% of the people having CVD can be attributed to hypertension.
c. Odds ratio for the participants:
The odds that a person with CVD has hypertension
¿ 281
300 =0.9367