CHRONIC ASTHMA 4inflammation of the airway(Bachert & Zhang, 2012). The other factor which may also responsible for precipitating asthma complications is stress. Although the mechanisms for this is not clearly established yet. But it may be due to increased production and release of pro-inflammatory cytokines.When asthma becomes severe by time due to inflammation, other complications also begins suchas hypersecretion of mucus, edema, and formation of mucus plugs in the airway.One of the reasons for hyperresponsiveness of airway may asthma. The mechanisms which are responsible for above pathology are dysfunctional neuro-regulation, inflammation, and structuralchanges.In some patients suffering from asthma, airflow obstruction may be reversible to some extent(Cardinale, Giordano, Chinellato & Tesse, 2013). The permanent structural modifications can occur. These changes are due to progressive lung dysfunction which is not prohibited by or can be reversed by current therapy. Airway remodeling includes an activation of several structural cells, with permanent changes that enhance the airflow obstruction and airway hyperresponsiveness. This leads to patient decreased response to therapy. The structural changes discussed above can be the sub-basement membrane thickening, airway hypertrophy of smooth muscles and hyperplasia, subepithelial fibrosis, proliferation of blood vessels and dilation, and mucus hypersecretion(Henderson, 2008).The following are the important points which should be always taken into consideration by nurses during health management of asthma patients:Nurses should put emphasis on long-term therapy which is ongoing.Nurses should take care of patients with moderate as well as severe asthma require inhaled anti-inflammatory therapy on daily basis to decrease asthma episodes.Discuss with the patient and concerned physician to

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