Breast Cancer Treatment and Research
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This assignment delves into various aspects of breast cancer treatment and research. It discusses different treatment modalities like adjuvant endocrine therapy, radiotherapy, and ovarian suppression. The importance of tumor-infiltrating lymphocytes (TILs) as a prognostic marker and potential therapeutic target is highlighted. The document also explores ongoing clinical trials and future research directions in breast cancer management.
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Table of Contents
INTRODUCTION...........................................................................................................................1
Main Body.......................................................................................................................................1
CONCLUSION................................................................................................................................4
REFERENCES................................................................................................................................1
INTRODUCTION...........................................................................................................................1
Main Body.......................................................................................................................................1
CONCLUSION................................................................................................................................4
REFERENCES................................................................................................................................1
INTRODUCTION
Health and social care determines different types of services to solve issues of people
within the enterprise. In this context, present report is based on essay which include case of
Marry and her disease (Salgado, Denkert and Perez, 2015). She is suffers emotional, cognitive
and behavioural responses which relates to her personnel life. Furthermore, risk and protective
factors create highly creates impact on her situation.
Main Body
In the present case Marry is suffers from crucial disease which create impact on her
personal life (Burandt, Grünert and Geist, 2016). In this way, following are such elements in
which response of Marry can be assess towards her disease:
Emotional response
Emotional response is refers through specific learned behaviour which include procedure
to understand the problem of people. In the present case study, due to suffer such crucial disease,
Marry face problem to deals with for growing their children. This is because, from last some
months, her husband is not live with her. In addition to this, at the time of her delivery no one
member from her family is with for caring Marry and their children. In this aspect, she is facing
issue to take care for herself and children (Burandt, Grünert and Geist, 2016). It creates problem
to deal in her life. It creates distress to Marry for enhance her understanding in term of delivering
intervention durst. It also reduces understanding power of people to make sure that effectiveness
can be occur at workplace. With the help of proper functioning, care providers can motivates her
for enhance emotions and psycho logistics pretreatment. It assists to prepare range of problems
that face by Marry in her life. Thus, patients can be prepare for solves emotional challenges.
Thus, she can reduce range of problems which includes anxiety, depression, obsessive
compulsive disorder and many other issue which can be often in emotional challenges (Burandt,
Grünert and Geist, 2016).
Cognitive response
In the present case, Marry is not knows about anyone in front of her so that it create
problem to make relation to the diagnosis. In this aspect, her experience is taken to deal with
situation of people. With the help of proper treatment, she can work on their children. Further,
thinking capacity of Marry is reduce due to suffering of cancer (Francis, Regan and Martino,
1
Health and social care determines different types of services to solve issues of people
within the enterprise. In this context, present report is based on essay which include case of
Marry and her disease (Salgado, Denkert and Perez, 2015). She is suffers emotional, cognitive
and behavioural responses which relates to her personnel life. Furthermore, risk and protective
factors create highly creates impact on her situation.
Main Body
In the present case Marry is suffers from crucial disease which create impact on her
personal life (Burandt, Grünert and Geist, 2016). In this way, following are such elements in
which response of Marry can be assess towards her disease:
Emotional response
Emotional response is refers through specific learned behaviour which include procedure
to understand the problem of people. In the present case study, due to suffer such crucial disease,
Marry face problem to deals with for growing their children. This is because, from last some
months, her husband is not live with her. In addition to this, at the time of her delivery no one
member from her family is with for caring Marry and their children. In this aspect, she is facing
issue to take care for herself and children (Burandt, Grünert and Geist, 2016). It creates problem
to deal in her life. It creates distress to Marry for enhance her understanding in term of delivering
intervention durst. It also reduces understanding power of people to make sure that effectiveness
can be occur at workplace. With the help of proper functioning, care providers can motivates her
for enhance emotions and psycho logistics pretreatment. It assists to prepare range of problems
that face by Marry in her life. Thus, patients can be prepare for solves emotional challenges.
Thus, she can reduce range of problems which includes anxiety, depression, obsessive
compulsive disorder and many other issue which can be often in emotional challenges (Burandt,
Grünert and Geist, 2016).
Cognitive response
In the present case, Marry is not knows about anyone in front of her so that it create
problem to make relation to the diagnosis. In this aspect, her experience is taken to deal with
situation of people. With the help of proper treatment, she can work on their children. Further,
thinking capacity of Marry is reduce due to suffering of cancer (Francis, Regan and Martino,
1
2015). Now she unable to feed their children due to breast cancer. Hence, it creates issue which
need to be solve for enhance empirical factual knowledge. When she knows that she is suffers to
cancer, it creates negative impact on her life to enhance their productivity. With the help of
emotionally challenges, components can be also included which need to be ascertain for
development and performances measurement (Francis, Regan and Martino, 2015). Marry is
unable to meet with her siblings and husband so that it creates problem which she is facing in
life. In respect to take care in proper way. Reaction of Marry has been change due to suffer
problem. Thus, it will create problem to make sure that guidance for her can be made through
maintains her outcomes and performances which is related to influence by different factors. It
includes unethical incidents which should be focus for ascertains outcomes and performances.
With the help of proper aspect, guidance is required which follows for determines specific
strategy that assist to solve her issue within the environment. In this way, she can provide proper
treatment towards herself which is very important to manage their personal life decisions
(Burandt, Grünert and Geist, 2016).
Behavioural response
In addition to this, behavioural response also create issue in Marry diagnosis. In this
aspect, she has responsibility to take proper care of their children which determines in positive
aspect. With the help of providing proper health services, she can work on growing their children
(Loi, Michiels and Piccart, 2014). In this aspect, results is created with developing outcomes and
her performances through she can provide feed her children. Due to children coming in 8th
month, Marry cannot take behavioural response to provide her effective and proper care. In this
aspect, it is very important to make effective results and performances for analysis issue which is
related to the behavioural responses. With combining such elements, it has been sure that people
are influences through determining connection with people. In this aspect, behaviour of Marry
has been changed due to facing problem in her life (Salgado, Denkert and Perez, 2015). In this
aspect, it is very important to negative impact need to be reduce that create problem to deals with
different elements. In this aspect, dimension also created which would be analysis the
performances and measurement.
In addition to this, there are also such risk elements occur which creates problem to
provide proper care to self and children (Tutt, Ellis and Dowsett, 2015). In case of Mary, it
creates various risk element in her life which are as follows:
2
need to be solve for enhance empirical factual knowledge. When she knows that she is suffers to
cancer, it creates negative impact on her life to enhance their productivity. With the help of
emotionally challenges, components can be also included which need to be ascertain for
development and performances measurement (Francis, Regan and Martino, 2015). Marry is
unable to meet with her siblings and husband so that it creates problem which she is facing in
life. In respect to take care in proper way. Reaction of Marry has been change due to suffer
problem. Thus, it will create problem to make sure that guidance for her can be made through
maintains her outcomes and performances which is related to influence by different factors. It
includes unethical incidents which should be focus for ascertains outcomes and performances.
With the help of proper aspect, guidance is required which follows for determines specific
strategy that assist to solve her issue within the environment. In this way, she can provide proper
treatment towards herself which is very important to manage their personal life decisions
(Burandt, Grünert and Geist, 2016).
Behavioural response
In addition to this, behavioural response also create issue in Marry diagnosis. In this
aspect, she has responsibility to take proper care of their children which determines in positive
aspect. With the help of providing proper health services, she can work on growing their children
(Loi, Michiels and Piccart, 2014). In this aspect, results is created with developing outcomes and
her performances through she can provide feed her children. Due to children coming in 8th
month, Marry cannot take behavioural response to provide her effective and proper care. In this
aspect, it is very important to make effective results and performances for analysis issue which is
related to the behavioural responses. With combining such elements, it has been sure that people
are influences through determining connection with people. In this aspect, behaviour of Marry
has been changed due to facing problem in her life (Salgado, Denkert and Perez, 2015). In this
aspect, it is very important to negative impact need to be reduce that create problem to deals with
different elements. In this aspect, dimension also created which would be analysis the
performances and measurement.
In addition to this, there are also such risk elements occur which creates problem to
provide proper care to self and children (Tutt, Ellis and Dowsett, 2015). In case of Mary, it
creates various risk element in her life which are as follows:
2
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Physical activity level
In respect to deal in daily life, Marry has problem to take care for hear. This is because, it
creates problem to make their personal decision delay due to worry and tension. In addition to
this, Marry is not living with any her sibling and husband so that it create problem to solve her
issue in effective manner. In physical activity level consist with reducing performances in day to
day life. In this aspect, risk need to be assess which frame for ascertain the effective results. With
the help of proper activity, physical outcomes are frames for determines effective results
(Burandt, Grünert and Geist, 2016).
Body weight
In this type of cancer, Marry suffers due to loss of hear weight that create weakness in her
life. This is because, it creates problem to deal with daily results and performances. With the
help of proper care she can enhance her understanding and outcomes level. In this way, she is
getting proper performances towards her children. In addition to this, loose body weight also
need to carry for undertake results and performances with developing outcomes. In this aspect, it
is very important to solve diagnosed with breast cancer which enhance risk (Donker, van
Tienhoven and Bouma, 2014).
Feed to her children
Breast cancer also create problem to feed children so that Marry unable to provide proper
care to her twins. This is because, her children are very small and due to coming in 8th month she
is unable to provide proper care regarding growing. Further, problem is also needs to take for
enhance performances. In this way, children are not growing effectively so that it creates
problem to provide proper feed at workplace to children. In this aspect, every person has
responsibility to make sure that children are not feeding by Marry. This is because, it creates
negative impact on the person to provides proper care and maintains in personal life. Thus, it is
need to be solved for children (Francis, Regan and Martino, 2015).
Financial risk
In order to reduce the problems, Marry is also unable to spend finance because she is not
living with her husband. In respect to meet with proper functioning, she is unable to work. This
is because, her children are small and she is also suffered from Breast cancer. It creates problem
to arrange finance. From some times she is also not contact with her any sibling physically. She
can contact with them only on Skype. Hence, it creates risk to provide proper treatment to her
3
In respect to deal in daily life, Marry has problem to take care for hear. This is because, it
creates problem to make their personal decision delay due to worry and tension. In addition to
this, Marry is not living with any her sibling and husband so that it create problem to solve her
issue in effective manner. In physical activity level consist with reducing performances in day to
day life. In this aspect, risk need to be assess which frame for ascertain the effective results. With
the help of proper activity, physical outcomes are frames for determines effective results
(Burandt, Grünert and Geist, 2016).
Body weight
In this type of cancer, Marry suffers due to loss of hear weight that create weakness in her
life. This is because, it creates problem to deal with daily results and performances. With the
help of proper care she can enhance her understanding and outcomes level. In this way, she is
getting proper performances towards her children. In addition to this, loose body weight also
need to carry for undertake results and performances with developing outcomes. In this aspect, it
is very important to solve diagnosed with breast cancer which enhance risk (Donker, van
Tienhoven and Bouma, 2014).
Feed to her children
Breast cancer also create problem to feed children so that Marry unable to provide proper
care to her twins. This is because, her children are very small and due to coming in 8th month she
is unable to provide proper care regarding growing. Further, problem is also needs to take for
enhance performances. In this way, children are not growing effectively so that it creates
problem to provide proper feed at workplace to children. In this aspect, every person has
responsibility to make sure that children are not feeding by Marry. This is because, it creates
negative impact on the person to provides proper care and maintains in personal life. Thus, it is
need to be solved for children (Francis, Regan and Martino, 2015).
Financial risk
In order to reduce the problems, Marry is also unable to spend finance because she is not
living with her husband. In respect to meet with proper functioning, she is unable to work. This
is because, her children are small and she is also suffered from Breast cancer. It creates problem
to arrange finance. From some times she is also not contact with her any sibling physically. She
can contact with them only on Skype. Hence, it creates risk to provide proper treatment to her
3
and children as well. Due to these problems, she is also facing some other issue like providing
food and other important things, etc. Marry is unable to carry her treatment and children as well
because it is not easily solved for ascertain outcomes and performances (Gnant, Mlineritsch and
Balic, 2015).
Proper care to them
Due to facing issue in breast cancer, Marry is also unable to deals with proper carrying of
people. Thus, it creates problem to solve this issue in effective manner. In respect to meet with
effective results, it is important to developing solution for solves breast cancer. In this way,
Marry cannot take any treatment without finance. When Marry has not enough money, she is
unable to determines her proper care for enhance their outcomes and performances. With the
help of treatment, she can live happily (Burstein, Temin and Stearns, 2014). In this aspect, Marry
can easily solves their issue which need to be ascertain for enhance understanding.
CONCLUSION
From the above report, it has been concluded that breast cancer is very crucial disease
which create problem to dealing in person life. This is because, it creates many other problems
which need to be solved for enhance understand and proper care of children. In this aspect, there
are various issues which need to be solved by Marry to enhance her productivity. With the help
of connection of people, there are such factors which create issue to dealing with outcomes,
furthermore, risk element also considering which also generate problem to solve the diseases
such as financial, feed to babies and many more elements.
4
food and other important things, etc. Marry is unable to carry her treatment and children as well
because it is not easily solved for ascertain outcomes and performances (Gnant, Mlineritsch and
Balic, 2015).
Proper care to them
Due to facing issue in breast cancer, Marry is also unable to deals with proper carrying of
people. Thus, it creates problem to solve this issue in effective manner. In respect to meet with
effective results, it is important to developing solution for solves breast cancer. In this way,
Marry cannot take any treatment without finance. When Marry has not enough money, she is
unable to determines her proper care for enhance their outcomes and performances. With the
help of treatment, she can live happily (Burstein, Temin and Stearns, 2014). In this aspect, Marry
can easily solves their issue which need to be ascertain for enhance understanding.
CONCLUSION
From the above report, it has been concluded that breast cancer is very crucial disease
which create problem to dealing in person life. This is because, it creates many other problems
which need to be solved for enhance understand and proper care of children. In this aspect, there
are various issues which need to be solved by Marry to enhance her productivity. With the help
of connection of people, there are such factors which create issue to dealing with outcomes,
furthermore, risk element also considering which also generate problem to solve the diseases
such as financial, feed to babies and many more elements.
4
5
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REFERENCES
Books and Journals
Burandt, E., Grünert, M. & Geist, S. (2016). Cyclin D1 gene amplification is highly
homogeneous in breast cancer. Breast Cancer. 23(1). 111-119.
Burstein, H. J., Temin, S. & Stearns, V. (2014). Adjuvant endocrine therapy for women with
hormone receptor–positive breast cancer: American Society of Clinical Oncology clinical
practice guideline focused update. Journal of Clinical Oncology. 32(21). 2255-2269.
Donker, M., van Tienhoven, G. & Bouma, W. H. (2014). Radiotherapy or surgery of the axilla
after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a
randomised, multicentre, open-label, phase 3 non-inferiority trial. The Lancet Oncology.
15(12). 1303-1310.
Francis, P. A., Regan, M. M. & Martino, S. (2015). Adjuvant ovarian suppression in
premenopausal breast cancer. New England Journal of Medicine. 372(5). 436-446.
Gnant, M., Mlineritsch, B. & Balic, M. (2015). Zoledronic acid combined with adjuvant
endocrine therapy of tamoxifen versus anastrozol plus ovarian function suppression in
premenopausal early breast cancer: final analysis of the Austrian Breast and Colorectal
Cancer Study Group Trial 12. Annals of Oncology. 26(2). 313-320.
Loi, S., Michiels, S. & Piccart, M. J. (2014). Tumor infiltrating lymphocytes are prognostic in
triple negative breast cancer and predictive for trastuzumab benefit in early breast cancer:
results from the FinHER trial. Annals of oncology. 25(8). 1544-1550.
Salgado, R., Denkert, C. & Perez, E. A. (2015). The evaluation of tumor-infiltrating
lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working
Group 2014. Annals of oncology. 26(2). 259-271.
Tutt, A., Ellis, P. & Dowsett, M. (2015). Abstract S3-01: the TNT trial: a randomized phase III
trial of carboplatin (C) compared with docetaxel (D) for patients with metastatic or
recurrent locally advanced triple negative or BRCA1/2 breast cancer (CRUK/07/012).
Books and Journals
Burandt, E., Grünert, M. & Geist, S. (2016). Cyclin D1 gene amplification is highly
homogeneous in breast cancer. Breast Cancer. 23(1). 111-119.
Burstein, H. J., Temin, S. & Stearns, V. (2014). Adjuvant endocrine therapy for women with
hormone receptor–positive breast cancer: American Society of Clinical Oncology clinical
practice guideline focused update. Journal of Clinical Oncology. 32(21). 2255-2269.
Donker, M., van Tienhoven, G. & Bouma, W. H. (2014). Radiotherapy or surgery of the axilla
after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a
randomised, multicentre, open-label, phase 3 non-inferiority trial. The Lancet Oncology.
15(12). 1303-1310.
Francis, P. A., Regan, M. M. & Martino, S. (2015). Adjuvant ovarian suppression in
premenopausal breast cancer. New England Journal of Medicine. 372(5). 436-446.
Gnant, M., Mlineritsch, B. & Balic, M. (2015). Zoledronic acid combined with adjuvant
endocrine therapy of tamoxifen versus anastrozol plus ovarian function suppression in
premenopausal early breast cancer: final analysis of the Austrian Breast and Colorectal
Cancer Study Group Trial 12. Annals of Oncology. 26(2). 313-320.
Loi, S., Michiels, S. & Piccart, M. J. (2014). Tumor infiltrating lymphocytes are prognostic in
triple negative breast cancer and predictive for trastuzumab benefit in early breast cancer:
results from the FinHER trial. Annals of oncology. 25(8). 1544-1550.
Salgado, R., Denkert, C. & Perez, E. A. (2015). The evaluation of tumor-infiltrating
lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working
Group 2014. Annals of oncology. 26(2). 259-271.
Tutt, A., Ellis, P. & Dowsett, M. (2015). Abstract S3-01: the TNT trial: a randomized phase III
trial of carboplatin (C) compared with docetaxel (D) for patients with metastatic or
recurrent locally advanced triple negative or BRCA1/2 breast cancer (CRUK/07/012).
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