This statistical study tests the influence of age, sex, systolic blood pressure, total serum cholesterol, current smoker, and diabetes on BMI of heart patients using the Framingham Heart Study dataset. The difference between mean BMI of the two genders, smokers and non-smokers, and diabetic and non-diabetic adults has been analysed. Regression analysis with ANOVA has been conducted to evaluate the impact of patient characteristics on BMI. The study concludes that age has a deterrent impact on BMI, whereas females are less prone to cardiovascular diseases compared to men. Systolic blood pressure positively impacts BMI indicating high BP to be a major reason behind cardio problems. Total serum cholesterol is a significant but slow impact factor. Smoking at present was found to have low BMI compared to non-smokers indicating requirement of further research. Diabetes is noted to have very high and significant impact on BMI in adverse way. Higher diabetes levels will certainly damage cardiovascular functionality.